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PDB: 242 件
1NJG
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Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit
分子名称: DNA polymerase III subunit gamma, SULFATE ION, ZINC ION
著者Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
登録日2002-12-30
公開日2003-04-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit
Structure, 11, 2003
1OE0
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CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP
分子名称: DEOXYRIBONUCLEOSIDE KINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
著者Mikkelsen, N.E, Johansson, K, Karlsson, A, Knecht, W, Andersen, G, Piskur, J, Munch-Petersen, B, Eklund, H.
登録日2003-03-17
公開日2003-10-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway:Studies of the Drosophila Deoxyribonucleoside Kinase
Biochemistry, 42, 2003
1XDV
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Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
分子名称: Son of sevenless protein homolog 1
著者Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
登録日2004-09-08
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1DKG
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CRYSTAL STRUCTURE OF THE NUCLEOTIDE EXCHANGE FACTOR GRPE BOUND TO THE ATPASE DOMAIN OF THE MOLECULAR CHAPERONE DNAK
分子名称: MOLECULAR CHAPERONE DNAK, NUCLEOTIDE EXCHANGE FACTOR GRPE
著者Harrison, C.J, Kuriyan, J.
登録日1997-02-13
公開日1997-08-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK.
Science, 276, 1997
1XXI
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ADP Bound E. coli Clamp Loader Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, DNA polymerase III, ...
著者Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
登録日2004-11-05
公開日2004-12-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
1XD2
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Crystal Structure of a ternary Ras:SOS:Ras*GDP complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
登録日2004-09-03
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
1NVU
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Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
登録日2003-02-04
公開日2003-04-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
1FJL
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HOMEODOMAIN FROM THE DROSOPHILA PAIRED PROTEIN BOUND TO A DNA OLIGONUCLEOTIDE
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*TP*CP*TP*GP*AP*TP*TP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*AP*AP*TP*CP*AP*GP*AP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*GP*TP*AP*AP*TP*CP*TP*GP*AP*TP*TP*AP*C)-3'), ...
著者Wilson, D.S, Guenther, B, Desplan, C, Kuriyan, J.
登録日1995-12-17
公開日1996-06-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA.
Cell(Cambridge,Mass.), 82, 1995
1D5A
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CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM
分子名称: MAGNESIUM ION, PROTEIN (DNA POLYMERASE), SULFATE ION
著者Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J.
登録日1999-10-06
公開日2000-03-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an archaebacterial DNA polymerase.
Structure Fold.Des., 7, 1999
2OIQ
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Crystal Structure of chicken c-Src kinase domain in complex with the cancer drug imatinib.
分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
著者Seeliger, M.A, Nagar, B, Frank, F, Cao, X, Henderson, M.N, Kuriyan, J.
登録日2007-01-11
公開日2007-03-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty.
Structure, 15, 2007
1XD4
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Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS)
分子名称: Son of sevenless protein homolog 1
著者Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J.
登録日2004-09-03
公開日2004-11-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Structural analysis of autoinhibition in the ras activator son of sevenless.
Cell(Cambridge,Mass.), 119, 2004
2OCP
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Crystal Structure of Human Deoxyguanosine Kinase
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxyguanosine kinase
著者Johansson, K, Ramaswamy, S, Ljungkrantz, C, Knecht, W, Piskur, J, Munch-Petersen, B, Eriksson, S, Eklund, H.
登録日2006-12-21
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Substrate Specificities of Cellular Deoxyribonucleoside Kinases.
Nat.Struct.Biol., 8, 2001
1XXH
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ATPgS Bound E. Coli Clamp Loader Complex
分子名称: DNA polymerase III subunit gamma, DNA polymerase III, delta prime subunit, ...
著者Kazmirski, S.L, Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J.
登録日2004-11-05
公開日2004-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex
Proc.Natl.Acad.Sci.USA, 101, 2004
1NVV
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Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
分子名称: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J.
登録日2003-02-04
公開日2003-04-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Cell(Cambridge,Mass.), 112, 2003
6AXF
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Structure of RasGRP2 in complex with Rap1B
分子名称: RAS guanyl-releasing protein 2, Ras-related protein Rap-1b
著者Kondo, Y, Iwig, J.S, Kuriyan, J.
登録日2017-09-06
公開日2017-10-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Elife, 6, 2017
2OZO
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BU of 2ozo by Molmil
Autoinhibited intact human ZAP-70
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tyrosine-protein kinase ZAP-70
著者Deindl, S, Kadlecek, T.A, Brdicka, T, Cao, X, Weiss, A, Kuriyan, J.
登録日2007-02-26
公開日2007-05-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70.
Cell(Cambridge,Mass.), 129, 2007
6AXG
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Structure of RasGRP4 in complex with HRas
分子名称: GTPase HRas, RAS guanyl-releasing protein 4
著者Kondo, Y, Iwig, J.S, Kuriyan, J.
登録日2017-09-06
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Elife, 6, 2017
1QCF
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CRYSTAL STRUCTURE OF HCK IN COMPLEX WITH A SRC FAMILY-SELECTIVE TYROSINE KINASE INHIBITOR
分子名称: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, Tyrosine-protein kinase HCK
著者Schindler, T, Sicheri, F, Pico, A, Gazit, A, Levitzki, A, Kuriyan, J.
登録日1999-05-04
公開日1999-06-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor.
Mol.Cell, 3, 1999
1DBH
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DBL AND PLECKSTRIN HOMOLOGY DOMAINS FROM HSOS1
分子名称: PROTEIN (HUMAN SOS 1)
著者Soisson, S.M, Kuriyan, J.
登録日1998-12-17
公開日1998-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.
Cell(Cambridge,Mass.), 95, 1998
1Q9C
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Crystal Structure of the Histone domain of Son of Sevenless
分子名称: Son of sevenless protein
著者Sondermann, H, Soisson, S.M, Bar-Sagi, D, Kuriyan, J.
登録日2003-08-24
公開日2003-12-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Tandem Histone Folds in the Structure of the N-terminal Segment of the Ras Activator Son of Sevenless
Structure, 11, 2003
2PNE
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Crystal Structure of the Snow Flea Antifreeze Protein
分子名称: 6.5 kDa glycine-rich antifreeze protein
著者Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M.
登録日2007-04-24
公開日2008-04-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers
J.Am.Chem.Soc., 130, 2008
5O9M
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Crystal structure of human Histamine-Releasing Factor (HRF/TCTP)containing a disulphide-linked dimer
分子名称: DI(HYDROXYETHYL)ETHER, Translationally-controlled tumor protein
著者Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M.
登録日2017-06-19
公開日2017-12-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation.
Mol. Immunol., 93, 2017
5O9L
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Crystal structure of human Histamine-Releasing Factor (HRF/TCTP)
分子名称: Translationally-controlled tumor protein
著者Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M.
登録日2017-06-19
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation.
Mol. Immunol., 93, 2017
2DYF
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Solution structure of the first WW domain of FBP11 / HYPA (FBP11 WW1) complexed with a PL (PPLP) motif peptide ligand
分子名称: Huntingtin-interacting protein HYPA/FBP11, PL (PPLP) motif peptide from Myosin tail region-interacting protein MTI1
著者Kato, Y, Miyakawa, T, Kurita, J, Tanokura, M.
登録日2006-09-11
公開日2006-10-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Complex structure of fbp11 ww1 and a pl ligand reveals the mechanism of proline-rich ligand recognition by group-II/III ww domains
To be Published
5O9K
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Crystal structure of Murine Histmaine-Releasing Factor (HRF/TCTP)
分子名称: GLYCEROL, Translationally-controlled tumor protein
著者Dore, K.A, Kashiwakura, J, McDonnell, J.M, Gould, H.J, Kawakami, T, Sutton, B.J, Davies, A.M.
登録日2017-06-19
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.014 Å)
主引用文献Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation.
Mol. Immunol., 93, 2017

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