5O9M

Crystal structure of human Histamine-Releasing Factor (HRF/TCTP)containing a disulphide-linked dimer

Summary for 5O9M

• Entry DOI: 10.2210/pdb5o9m/pdb
• Descriptor: Translationally-controlled tumor protein, DI(HYDROXYETHYL)ETHER (3 entities in total)
• Functional Keywords: immunoglobulin e, allergy, histamine releasing factor, tctp, hrf, p23, p21, fortilin, immune system
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P13693
• Total number of polymer chains: 2
• Total formula weight: 41487.12

Authors

Dore, K.A.,Kashiwakura, J.,McDonnell, J.M.,Gould, H.J.,Kawakami, T.,Sutton, B.J.,Davies, A.M. (deposition date: 2017-06-19, release date: 2017-12-20, Last modification date: 2024-01-17)

• Primary citation: Dore, K.A.,Kashiwakura, J.I.,McDonnell, J.M.,Gould, H.J.,Kawakami, T.,Sutton, B.J.,Davies, A.M.; Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation.; Mol. Immunol., 93:216-222, 2017; PubMed: 29216544; DOI: 10.1016/j.molimm.2017.11.022

Experimental method

X-RAY DIFFRACTION (1.4 Å)