1OE0

CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP

Summary for 1OE0

Related1J90
DescriptorDEOXYRIBONUCLEOSIDE KINASE, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordstransferase, drosophila, deoxyribonucleoside kinase, dttp, complex, feedback inhibition, salvage pathway
Biological sourceDROSOPHILA MELANOGASTER (FRUIT FLY)
Total number of polymer chains4
Total molecular weight109652.72
Authors
Mikkelsen, N.E.,Johansson, K.,Karlsson, A.,Knecht, W.,Andersen, G.,Piskur, J.,Munch-Petersen, B.,Eklund, H. (deposition date: 2003-03-17, release date: 2003-10-23, Last modification date: 2011-07-13)
Primary citation
Mikkelsen, N.E.,Johansson, K.,Karlsson, A.,Knecht, W.,Andersen, G.,Piskur, J.,Munch-Petersen, B.,Eklund, H.
Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway:Studies of the Drosophila Deoxyribonucleoside Kinase
Biochemistry, 42:5706-, 2003
PubMed: 12741827 (PDB entries with the same primary citation)
DOI: 10.1021/BI0340043
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.236121.1%3.7%6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload