3FV4
| Thermolysin inhibition | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Englert, L, Biela, A, Heine, A, Klebe, G. | 登録日 | 2009-01-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Displacement of disordered water molecules from hydrophobic pocket creates enthalpic signature: binding of phosphonamidate to the S1'-pocket of thermolysin. Biochim.Biophys.Acta, 1800, 2010
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3FVP
| Thermolysin inhibition | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Englert, L, Biela, A, Heine, A, Klebe, G. | 登録日 | 2009-01-16 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Thermolysin inhibition To be Published
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2PWU
| tRNA guanine transglycosylase in complex with guanine | 分子名称: | GLYCEROL, GUANINE, Queuine tRNA-ribosyltransferase, ... | 著者 | Tidten, N, Heine, A, Reuter, K, Klebe, G. | 登録日 | 2007-05-13 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies. J.Mol.Biol., 374, 2007
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3FXS
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3EIM
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2PWV
| tRNA guanine transglycosylase E235Q mutant in complex with preQ0 | 分子名称: | 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Tidten, N, Stengl, B, Heine, A, Reuter, K, Klebe, G. | 登録日 | 2007-05-13 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies. J.Mol.Biol., 374, 2007
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3DT0
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2QII
| Crystal Structure Of tRNA-Guanine Transglycosylase (TGT) From Zymomonas mobilis Complexed With Archaeosine Precursor, Preq0 | 分子名称: | 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Tidten, N, Brenk, R, Heine, A, Reuter, K, Klebe, G. | 登録日 | 2007-07-04 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies. J.Mol.Biol., 374, 2007
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4Y3G
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4Y4E
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4Y3N
| Endothiapepsin in complex with fragment 273 | 分子名称: | 2-[(1S)-2-acetyl-1,2-dihydroisoquinolin-1-yl]-N,N-dimethylacetamide, ACETATE ION, Endothiapepsin, ... | 著者 | Krimmer, S.G, Heine, A, Klebe, G. | 登録日 | 2015-02-10 | 公開日 | 2016-02-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Crystallographic Fragment Screening of an Entire Library To Be Published
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2Z1X
| tRNA guanine transglycosylase E235Q mutant in complex with preQ1 | 分子名称: | 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Tidten, N, Stengl, B, Heine, A, Garcia, G.A, Klebe, G, Reuter, K. | 登録日 | 2007-05-16 | 公開日 | 2007-11-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies J.Mol.Biol., 374, 2007
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4Q8N
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4QBX
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4Q7B
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4Y3S
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4Y47
| Endothiapepsin in complex with fragment 162 | 分子名称: | 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl)butanamide, ACETATE ION, Endothiapepsin, ... | 著者 | Krimmer, S.G, Krug, M, Uehlein, M, Heine, A, Klebe, G. | 登録日 | 2015-02-10 | 公開日 | 2016-02-17 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Crystallographic Fragment Screening of an Entire Library To Be Published
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4Y44
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4QR6
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4PRR
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4PRT
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4PR4
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4PUW
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2Z1W
| tRNA guanine transglycosylase TGT E235Q mutant in complex with BDI (2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE) | 分子名称: | 2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Tidten, N, Stengl, B, Heine, A, Garcia, G.A, Klebe, G, Reuter, K. | 登録日 | 2007-05-16 | 公開日 | 2007-11-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies J.Mol.Biol., 374, 2007
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4PUU
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