8AE9
Human Aldose Reductase in Complex with a Hydroxyphenyl-Thiophen-Acid Inhibitor (Schl32357)
Summary for 8AE9
Entry DOI | 10.2210/pdb8ae9/pdb |
Descriptor | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 5-(5-(3-hydroxyphenyl)thiophen-2-yl)pentanoic acid, ... (5 entities in total) |
Functional Keywords | human aldose reductase, har, aldo-keto-reductase, schl32357 ligand, nadp+, diabetes, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 36996.23 |
Authors | |
Primary citation | Hubert, L.-S.,Heine, A.,Klebe, G.,Reul, S. Human Aldose Reductase in Complex with a Hydroxyphenyl-Thiophen-Acid Inhibitor (Schl32357) To Be Published, |
Experimental method | X-RAY DIFFRACTION (0.95 Å) |
Structure validation
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