8B34

Structure of Human Aldose Reductase Mutant A299G with a Citrate Molecule Bound in the Anion Binding Pocket

Summary for 8B34

• Entry DOI: 10.2210/pdb8b34/pdb
• Descriptor: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRIC ACID, ... (4 entities in total)
• Functional Keywords: human aldose reductase, har, aldo-keto-reductase, mutant a299g, transient pocket, nadp+, diabetes, citrate, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37237.20

Authors

Hubert, L.-S.,Heine, A.,Klebe, G. (deposition date: 2022-09-15, release date: 2023-09-27)

• Primary citation: Hubert, L.-S.,Heine, A.,Klebe, G.; Structure of Human Aldose Reductase Mutant A299G with a Citrate Molecule Bound in the Anion Binding Pocket; To Be Published,

Experimental method

X-RAY DIFFRACTION (0.97 Å)