8A4N
Structure of Human Aldose Reductase Mutant L300G with a Citrate Molecule Bound in the Anion Binding Pocket
Summary for 8A4N
Entry DOI | 10.2210/pdb8a4n/pdb |
Descriptor | Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRIC ACID, ... (4 entities in total) |
Functional Keywords | human aldose reductase, har, aldo-keto-reductase, l300g mutant, citrate, nadp+, diabetes, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 36969.89 |
Authors | Hubert, L.-S.,Heine, A.,Klebe, G. (deposition date: 2022-06-13, release date: 2023-07-05, Last modification date: 2024-02-07) |
Primary citation | Hubert, L.-S.,Heine, A.,Klebe, G. Structure of Human Aldose Reductase Mutant L300G with a Citrate Molecule Bound in the Anion Binding Pocket To Be Published, |
Experimental method | X-RAY DIFFRACTION (0.93 Å) |
Structure validation
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