8AUU

Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)

Summary for 8AUU

• Entry DOI: 10.2210/pdb8auu/pdb
• Descriptor: Aldo-keto reductase family 1 member B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid, ... (5 entities in total)
• Functional Keywords: human aldose reductase, har, aldo-keto-reductase, a299g mutant, idd_06, nadp+, diabetes, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37168.12

Authors

Hubert, L.-S.,Heine, A.,Klebe, G. (deposition date: 2022-08-25, release date: 2023-09-06)

• Primary citation: Hubert, L.-S.,Heine, A.,Klebe, G.,Scheer, F.,Diederich, W.; Human Aldose Reductase Mutant A299G in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid); To Be Published,

Experimental method

X-RAY DIFFRACTION (0.95 Å)