3F28

Thermolysin inhibition

Summary for 3F28

• Entry DOI: 10.2210/pdb3f28/pdb
• Related: 1TMN 3F2P 8TLN
• Descriptor: Thermolysin, CALCIUM ION, ZINC ION, ... (5 entities in total)
• Functional Keywords: protein fragment complex, calcium, hydrolase, metal-binding, metalloprotease, protease, secreted, zinc, zymogen
• Biological source: Bacillus thermoproteolyticus
• Total number of polymer chains: 1
• Total formula weight: 34808.25

Authors

Englert, L.,Heine, A.,Klebe, G. (deposition date: 2008-10-29, release date: 2009-11-17, Last modification date: 2023-09-06)

• Primary citation: Englert, L.,Silber, K.,Steuber, H.,Brass, S.,Over, B.,Gerber, H.D.,Heine, A.,Diederich, W.E.,Klebe, G.; Fragment-Based Lead Discovery: Screening and Optimizing Fragments for Thermolysin Inhibition.; Chemmedchem, 5:930-940, 2010; PubMed: 20394106; DOI: 10.1002/cmdc.201000084

Experimental method

X-RAY DIFFRACTION (1.68 Å)