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PDB: 137 件

7TO9
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BRD3-BD1 in complex with RaPID linear peptide 2xAcK.4xE (diAcK.4xE)
分子名称: 2xAcK.4xE (diAcK.4xE), Bromodomain-containing protein 3, GLYCEROL
著者Mackay, J.P, Low, J.K.K, Patel, K.
登録日2022-01-23
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome.
J.Biol.Chem., 299, 2023
7TO7
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BRD3-BD1 in complex with RaPID linear peptide 1xAcK.4XE (monoAcK.4xE)
分子名称: 1xAcK.4xE (monoAcK.4xE), Bromodomain-containing protein 3, GLYCEROL
著者Mackay, J.P, Low, J.K.K, Patel, K.
登録日2022-01-23
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome.
J.Biol.Chem., 299, 2023
7T2Q
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PEGylated Calmodulin-1 (K148U)
分子名称: CALCIUM ION, Calmodulin-1, MAGNESIUM ION, ...
著者Mackay, J.P, Payne, R.J, Patel, K, Dowman, L.J.
登録日2021-12-06
公開日2022-10-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine.
Nat Commun, 13, 2022
2HI3
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Solution structure of the homeodomain-only protein HOP
分子名称: Homeodomain-only protein
著者Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W.
登録日2006-06-28
公開日2007-01-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Analysis of the structure and function of the transcriptional coregulator HOP
Biochemistry, 45, 2006
2MPL
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BU of 2mpl by Molmil
Solution structure of the PR domain of FOG-1
分子名称: Zinc finger protein ZFPM1
著者Mackay, J.P, Clifton, M.K, Westman, B.J, Blobel, G.A.
登録日2014-05-26
公開日2014-10-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Identification and Structure of an N-Terminal PR Domain Show that FOG1 Is a Member of the PRDM Family of Proteins.
Plos One, 9, 2014
2RPN
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A crucial role for high intrinsic specificity in the function of yeast SH3 domains
分子名称: Actin-binding protein, Actin-regulating kinase 1
著者Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A.
登録日2008-06-12
公開日2009-06-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p
J.Biol.Chem., 284, 2009
6UK1
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Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Wang, C, Vorobiev, S.M, Vernon, R.M, Khazanov, N, Senderowitz, H, Forman-Kay, J.D, Hunt, J.F.
登録日2019-10-03
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation
To Be Published
4TRX
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BU of 4trx by Molmil
HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF REDUCED RECOMBINANT HUMAN THIOREDOXIN IN SOLUTION
分子名称: THIOREDOXIN
著者Forman-Kay, J.D, Clore, G.M, Gronenborn, A.M.
登録日1990-12-17
公開日1992-01-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Biochemistry, 30, 1991
3TRX
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BU of 3trx by Molmil
HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF REDUCED RECOMBINANT HUMAN THIOREDOXIN IN SOLUTION
分子名称: THIOREDOXIN
著者Forman-Kay, J.D, Clore, G.M, Gronenborn, A.M.
登録日1990-12-17
公開日1992-01-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Biochemistry, 30, 1991
1EZP
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BU of 1ezp by Molmil
GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS
分子名称: MALTODEXTRIN BINDING PERIPLASMIC PROTEIN
著者Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E.
登録日2000-05-11
公開日2001-05-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein.
J.Mol.Biol., 300, 2000
1DDM
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SOLUTION STRUCTURE OF THE NUMB PTB DOMAIN COMPLEXED TO A NAK PEPTIDE
分子名称: NUMB ASSOCIATE KINASE, NUMB PROTEIN
著者Zwahlen, C, Li, S.C, Kay, L.E, Pawson, T, Forman-Kay, J.D.
登録日1999-11-11
公開日2000-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb.
EMBO J., 19, 2000
1EZO
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GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN
著者Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E.
登録日2000-05-11
公開日2001-05-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein.
J.Mol.Biol., 300, 2000
1KA7
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BU of 1ka7 by Molmil
SAP/SH2D1A bound to peptide n-Y-c
分子名称: SH2 DOMAIN PROTEIN 1A, peptide n-Y-c
著者Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C.
登録日2001-10-31
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
1KA6
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SAP/SH2D1A bound to peptide n-pY
分子名称: SH2 DOMAIN PROTEIN 1A, peptide n-pY
著者Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C.
登録日2001-10-31
公開日2001-11-07
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
2MX4
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BU of 2mx4 by Molmil
NMR structure of Phosphorylated 4E-BP2
分子名称: Eukaryotic translation initiation factor 4E-binding protein 2
著者Bah, A, Forman-Kay, J, Vernon, R, Siddiqui, Z, Krzeminski, M, Muhandiram, R, Zhao, C, Sonenberg, N, Kay, L.
登録日2014-12-10
公開日2015-01-07
最終更新日2015-03-18
実験手法SOLUTION NMR
主引用文献Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch.
Nature, 519, 2015
2NMB
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BU of 2nmb by Molmil
DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES.
分子名称: PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN)
著者Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D.
登録日1998-10-29
公開日1998-11-04
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.
Nat.Struct.Biol., 5, 1998
2PLE
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BU of 2ple by Molmil
NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE
分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF
著者Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D.
登録日1994-08-19
公開日1995-01-26
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
2PLD
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BU of 2pld by Molmil
NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE
分子名称: PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF
著者Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D.
登録日1994-08-19
公開日1995-01-26
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
2KIS
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BU of 2kis by Molmil
Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker
分子名称: Transcription elongation regulator 1
著者Murphy, J.M, Hansen, D, Wiesner, S, Muhandiram, D, Borg, M, Smith, M.J, Sicheri, F, Kay, L.E, Forman-Kay, J.D, Pawson, T.
登録日2009-05-08
公開日2009-09-08
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays.
J.Mol.Biol., 393, 2009
1JU5
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Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy
分子名称: Abl, Crk
著者Donaldson, L.W, Pawson, T, Kay, L.E, Forman-Kay, J.D.
登録日2001-08-23
公開日2002-11-06
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
Proc.Natl.Acad.Sci.USA, 99, 2002
3V7D
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BU of 3v7d by Molmil
Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex
分子名称: Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1
著者Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M.
登録日2011-12-20
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109, 2012
1MM5
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BU of 1mm5 by Molmil
Solution NMR structure of the outer membrane enzyme PagP in OG micelles
分子名称: CrcA protein
著者Hwang, P.M, Choy, W.-Y, Lo, E.I, Chen, L, Forman-Kay, J.D, Raetz, C.R.H, Prive, G.G, Bishop, R.E, Kay, L.E.
登録日2002-09-03
公開日2002-09-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR
Proc.Natl.Acad.Sci.USA, 99, 2002
1MM4
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Solution NMR structure of the outer membrane enzyme PagP in DPC micelles
分子名称: CrcA protein
著者Hwang, P.M, Choy, W.-Y, Lo, E.I, Chen, L, Forman-Kay, J.D, Raetz, C.R.H, Prive, G.G, Bishop, R.E, Kay, L.E.
登録日2002-09-03
公開日2002-09-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR
Proc.Natl.Acad.Sci.USA, 99, 2002
2DJY
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Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex
分子名称: Mothers against decapentaplegic homolog 7, Smad ubiquitination regulatory factor 2
著者Chong, P.A, Lin, H, Wrana, J.L, Forman-Kay, J.D.
登録日2006-04-06
公開日2006-05-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2.
J.Biol.Chem., 281, 2006
2AZV
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Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (calculated without NOEs)
分子名称: SH2-SH3 adapter protein drk
著者Bezsonova, I, Singer, A.U, Choy, W.-Y, Tollinger, M, Forman-Kay, J.D.
登録日2005-09-12
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant
Biochemistry, 44, 2005

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