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PDB: 381 件
2YPK
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BU of 2ypk by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, ...
著者Stewart-Jones, G.B, Simpson, P, Van Der Merwe, P.A, Easterbrook, P, Mcmichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
登録日2012-10-30
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
5BQE
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BU of 5bqe by Molmil
Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 -Methylated form
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPU
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Crystal structure of Norrin, a Wnt signalling activator, Crystal Form I
分子名称: (GGL)EEE, (GGL)EEEEEE, Norrin
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQB
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BU of 5bqb by Molmil
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form III
分子名称: CHLORIDE ION, CITRIC ACID, Norrin
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
2YPL
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BU of 2ypl by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
分子名称: AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ...
著者Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
登録日2012-10-30
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
5BQ8
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BU of 5bq8 by Molmil
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form II
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Norrin
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPB
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BU of 5bpb by Molmil
Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form I
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-27
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BPQ
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Crystal structure of the cysteine-rich domain of human Frizzled 4 - Crystal Form II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Frizzled-4
著者Chang, T.-H, Hsieh, F.-L, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
5BQC
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BU of 5bqc by Molmil
Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 and sucrose octasulfate
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, ...
著者Chang, T.-H, Hsieh, F.-L, Zebisch, M, Harlos, K, Jones, E.Y.
登録日2015-05-28
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4, 2015
6FKM
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BU of 6fkm by Molmil
Drosophila Plexin A in complex with Semaphorin 1b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
著者Rozbesky, D, Harlos, K, Jones, E.Y.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
6FKK
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BU of 6fkk by Molmil
Drosophila Semaphorin 1b, extracellular domains 1-2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rozbesky, D, Harlos, K, Jones, E.Y.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning.
Nat Commun, 10, 2019
6FKN
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BU of 6fkn by Molmil
Drosophila Plexin A in complex with Semaphorin 1b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
著者Rozbesky, D, Harlos, K, Jones, E.Y.
登録日2018-01-24
公開日2019-02-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4.801 Å)
主引用文献Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
6TR5
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BU of 6tr5 by Molmil
Melatonin-Notum complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.509 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6TR7
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BU of 6tr7 by Molmil
N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide-Notum complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6GBI
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BU of 6gbi by Molmil
Wnt signalling
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ly6/PLAUR domain-containing protein 6, ...
著者Zhao, Y, Jones, E.Y.
登録日2018-04-14
公開日2018-08-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure of the Wnt signaling enhancer LYPD6 and its interactions with the Wnt coreceptor LRP6.
FEBS Lett., 592, 2018
6GGM
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BU of 6ggm by Molmil
HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P2-Phe.
分子名称: Beta-2-microglobulin, MHC class I antigen, Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-ALA-PRO-LEU-LEU), ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-03
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.734 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GH4
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BU of 6gh4 by Molmil
HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P2-Gln.
分子名称: ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU, Beta-2-microglobulin, MHC class I antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6TR6
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BU of 6tr6 by Molmil
N-acetylserotonin-Notum complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
著者Zhao, Y, Jones, E.Y.
登録日2019-12-17
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6GH1
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BU of 6gh1 by Molmil
HLA-E*01:03 in complex with Mtb44
分子名称: Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], MHC class I antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GHN
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BU of 6ghn by Molmil
HLA-E*01:03 in complex with the Mtb44 peptide variant: Mtb44*P9-Phe.
分子名称: ARG-LEU-PRO-ALA-LYS-ALA-PRO-LEU-PHE, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-08
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.542 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
6GL1
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BU of 6gl1 by Molmil
HLA-E*01:03 in complex with the HIV epitope, RL9HIV
分子名称: ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, Beta-2-microglobulin, MHC class I antigen, ...
著者Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K.
登録日2018-05-22
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9, 2018
1HNF
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BU of 1hnf by Molmil
CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD2, SODIUM ION
著者Bodian, D.L, Jones, E.Y, Harlos, K, Stuart, D.I, Davis, S.J.
登録日1994-08-10
公開日1995-02-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure, 2, 1994
1OGA
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BU of 1oga by Molmil
A structural basis for immunodominant human T-cell receptor recognition.
分子名称: BETA-2-MICROGLOBULIN, GILGFVFTL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
著者Stewart-Jones, G.B.E, McMichael, A.J, Bell, J.I, Stuart, D.I, Jones, E.Y.
登録日2003-04-28
公開日2003-06-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Structural Basis for Immunodominant Human T Cell Receptor Recognition
Nat.Immunol., 4, 2003
3MFF
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BU of 3mff by Molmil
1F1E8hu TCR
分子名称: ARGININE, GLYCEROL, T cell receptor alpha chain, ...
著者van Boxel, G.I, Holmes, S, Fugger, L, Jones, E.Y.
登録日2010-04-02
公開日2010-06-02
最終更新日2014-03-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An alternative conformation of the T-cell receptor alpha constant region
J.Mol.Biol., 400, 2010
3P56
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BU of 3p56 by Molmil
The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
分子名称: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
著者Bubeck, D, Graham, S.C, Jones, E.Y.
登録日2010-10-08
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.06 Å)
主引用文献The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011

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件を2024-09-04に公開中

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