Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5BQC

Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 and sucrose octasulfate

Summary for 5BQC
Entry DOI10.2210/pdb5bqc/pdb
Related5BPB 5BPQ 5BPU 5BQ8 5BQB
Related PRD IDPRD_900013
DescriptorFrizzled-4, Norrin, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywordswnt signalling pathway, norrie disease protein, glycoprotein, g protein coupled receptor, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight31745.16
Authors
Chang, T.-H.,Hsieh, F.-L.,Zebisch, M.,Harlos, K.,Jones, E.Y. (deposition date: 2015-05-28, release date: 2015-07-01, Last modification date: 2024-01-10)
Primary citationChang, T.H.,Hsieh, F.L.,Zebisch, M.,Harlos, K.,Elegheert, J.,Jones, E.Y.
Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.
Elife, 4:e06554-, 2015
Cited by
PubMed: 26158506
DOI: 10.7554/eLife.06554
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon