5BQB
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form III
Summary for 5BQB
Entry DOI | 10.2210/pdb5bqb/pdb |
Related | 4MY2 5BPU 5BQ8 |
Descriptor | Norrin, CITRIC ACID, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | wnt signalling pathway, norrie disease protein, cystine-knot like growth factor, ligand for frizzled 4 receptor, signaling protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : Q00604 |
Total number of polymer chains | 4 |
Total formula weight | 55298.23 |
Authors | Chang, T.-H.,Hsieh, F.-L.,Harlos, K.,Jones, E.Y. (deposition date: 2015-05-28, release date: 2015-07-01, Last modification date: 2024-01-10) |
Primary citation | Chang, T.H.,Hsieh, F.L.,Zebisch, M.,Harlos, K.,Elegheert, J.,Jones, E.Y. Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. Elife, 4:e06554-, 2015 Cited by PubMed: 26158506DOI: 10.7554/eLife.06554 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report