5BQB
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form III
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Norrin | polymer | 122 | 13614.7 | 4 | UniProt (Q00604) Pfam (PF00007) | Homo sapiens (Human) | Norrie disease protein,X-linked exudative vitreoretinopathy 2 protein |
| 2 | E, F, H, I (A, C) | CITRIC ACID | non-polymer | 192.1 | 4 | Chemie (CIT) | |||
| 3 | G, J (A, D) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 25 - 133 (UniProt: Q00604)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 134 | - | expression tag |
| Thr 135 | - | expression tag |
| Glu 136 | - | expression tag |
| Thr 137 | - | expression tag |
| Ser 138 | - | expression tag |
| Gln 139 | - | expression tag |
| Val 140 | - | expression tag |
| Ala 141 | - | expression tag |
| Pro 142 | - | expression tag |
| Ala 143 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54458.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 839.4 | |
| All* | Total formula weight | 55298.2 |
