5BQB

Crystal structure of Norrin, a Wnt signalling activator, Crystal Form III

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Norrin	polymer	122	13614.7	4	UniProt (Q00604) Pfam (PF00007) In PDB	Homo sapiens (Human)	Norrie disease protein,X-linked exudative vitreoretinopathy 2 protein
2	A, C	CITRIC ACID	non-polymer		192.1	4	Chemie (CIT)
3	A, D	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4		water	water		18.0	72	Chemie (HOH)

Sequence modifications

A, B, C, D: 25 - 133 (UniProt: Q00604)

PDB	External Database	Details
Gly 22	-	expression tag
Pro 23	-	expression tag
Gly 24	-	expression tag
Gly 134	-	expression tag
Thr 135	-	expression tag
Glu 136	-	expression tag
Thr 137	-	expression tag
Ser 138	-	expression tag
Gln 139	-	expression tag
Val 140	-	expression tag
Ala 141	-	expression tag
Pro 142	-	expression tag
Ala 143	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	54458.8
Non-Polymers*	Number of molecules	6
	Total formula weight	839.4
All*	Total formula weight	55298.2

*Water molecules are not included.