5BQE

Crystal structure of Norrin in complex with the cysteine-rich domain of Frizzled 4 -Methylated form

Summary for 5BQE

• Entry DOI: 10.2210/pdb5bqe/pdb
• Related: 5BPB 5BPQ 5BPU 5BQ8 5BQB 5BQC
• Descriptor: Norrin, Frizzled-4, 2-(2-METHOXYETHOXY)ETHANOL, ... (7 entities in total)
• Functional Keywords: wnt signalling pathway, norrie disease protein, glycoprotein, g protein coupled receptor, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 44714.02

Authors

Chang, T.-H.,Hsieh, F.-L.,Harlos, K.,Jones, E.Y. (deposition date: 2015-05-28, release date: 2015-07-01, Last modification date: 2024-01-10)

• Primary citation: Chang, T.H.,Hsieh, F.L.,Zebisch, M.,Harlos, K.,Elegheert, J.,Jones, E.Y.; Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan.; Elife, 4:e06554-, 2015; PubMed: 26158506; DOI: 10.7554/eLife.06554

Experimental method

X-RAY DIFFRACTION (2.3 Å)