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PDB: 248 件

7VM6
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BU of 7vm6 by Molmil
Crystal structure of uPA in complex with 6-amidino-2-naphthol
分子名称: 6-oxidanylnaphthalene-2-carboximidamide, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Jiang, L.G, Huang, M.D.
登録日2021-10-07
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM7
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BU of 7vm7 by Molmil
Crystal structure of inactive uPA in complex with nafamostat
分子名称: (6-carbamimidoylnaphthalen-2-yl) 4-carbamimidamidobenzoate, Urokinase-type plasminogen activator chain B
著者Jiang, L.G, Huang, M.D.
登録日2021-10-07
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
2N3X
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BU of 2n3x by Molmil
Solution Structure of TDP-43 Amyloidogenic Core Region
分子名称: TAR DNA-binding protein 43
著者Jiang, L, Zhao, J, Zhou, C, Hu, H.
登録日2015-06-11
公開日2016-04-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Sci Rep, 6, 2016
2N4H
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BU of 2n4h by Molmil
Solution Structure of the Q343R Mutant of TDP-43 Amyloidogenic Core Region
分子名称: TAR DNA-binding protein 43
著者Jiang, L, Zhao, J, Hu, H.
登録日2015-06-18
公開日2016-04-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Sci Rep, 6, 2016
2N4G
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BU of 2n4g by Molmil
Solution Structure of the G335D Mutant of TDP-43 Amyloidogenic Core Region
分子名称: TAR DNA-binding protein 43
著者Jiang, L, Zhao, J, Hu, H.
登録日2015-06-17
公開日2016-04-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Sci Rep, 6, 2016
5ZRM
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BU of 5zrm by Molmil
Phosphoglycerate mutase 1 complexed with a small molecule inhibitor In-AC
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[(3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl)sulfamoyl]phenyl acetate, CHLORIDE ION, ...
著者Jiang, L.L, Zhou, L.
登録日2018-04-24
公開日2019-05-01
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Phosphoglycerate mutase 1 complexed with a small molecule inhibitor In-AC
To Be Published
5ZS7
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BU of 5zs7 by Molmil
Acetylation of lysine 100 in Phosphoglycerate mutase 1
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Phosphoglycerate mutase 1
著者Jiang, L.L, Zhou, L.
登録日2018-04-28
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Acetylation of lysine 100 in Phosphoglycerate mutase 1
To Be Published
3BBX
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BU of 3bbx by Molmil
The Hsp15 protein fitted into the low resolution Cryo-EM map of the 50S.nc-tRNA.Hsp15 complex
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Jiang, L, Abrahams, J.P.
登録日2007-11-11
公開日2008-10-21
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15.
J.Mol.Biol., 386, 2009
5Y2I
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BU of 5y2i by Molmil
Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor PGMI-004A
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)-~{N}-[4-(trifluoromethyl)phenyl]anthracene-2-sulfonamide, CHLORIDE ION, ...
著者Jiang, L, Zhou, L.
登録日2017-07-26
公開日2018-08-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.917 Å)
主引用文献Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor PGMI-004A
To Be Published
5ZS8
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BU of 5zs8 by Molmil
Acetylation of lysine 100 of Phosphoglycerate mutase 1 complexed with KH_ol
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, N-(3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl)-2-hydroxybenzene-1-sulfonamide, ...
著者Jiang, L.L, Zhou, L.
登録日2018-04-28
公開日2019-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Acetylation of lysine 100 of Phosphoglycerate mutase 1 complexed with KH_ol
To Be Published
3KID
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BU of 3kid by Molmil
The Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
分子名称: Urokinase-type plasminogen activator, ethyl 2-amino-1,3-benzothiazole-6-carboxylate
著者Jiang, L.-G, Yu, H.Y, Yuan, C, Wang, J.D, Chen, L.Q, Meehan, E.J, Huang, Z.-X, Huang, M.-D.
登録日2009-11-01
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
CHIN.J.STRUCT.CHEM., 28, 2009
4DW2
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BU of 4dw2 by Molmil
The crystal structure of uPA in complex with the Fab fragment of mAb-112
分子名称: Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
登録日2012-02-24
公開日2013-01-16
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
5XG4
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BU of 5xg4 by Molmil
Crystal structure of uPA in complex with quercetin
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, Urokinase-type plasminogen activator
著者Jiang, L, Huang, M.
登録日2017-04-11
公開日2017-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A structural mechanism of flavonoids in inhibiting serine proteases
Food Funct, 8, 2017
1TOB
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BU of 1tob by Molmil
SACCHARIDE-RNA RECOGNITION IN AN AMINOGLYCOSIDE ANTIBIOTIC-RNA APTAMER COMPLEX, NMR, 7 STRUCTURES
分子名称: 1,3-DIAMINO-5,6-DIHYDROXYCYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ...
著者Jiang, L, Suri, A.K, Fiala, R, Patel, D.J.
登録日1996-12-12
公開日1997-06-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex.
Chem.Biol., 4, 1997
4X1N
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BU of 4x1n by Molmil
The crystal structure of mupain-1-16 in complex with murinised human uPA at pH7.4
分子名称: Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide
著者Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M.
登録日2014-11-25
公開日2015-03-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility.
Plos One, 9, 2014
4NK4
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BU of 4nk4 by Molmil
Crystal structure of FabI from Candidatus Liberibacter asiaticus
分子名称: DI(HYDROXYETHYL)ETHER, Enoyl-[acyl-carrier-protein] reductase [NADH]
著者Jiang, L, Gao, Z.Q, Dong, Y.H.
登録日2013-11-12
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures and kinetic properties of enoyl-acyl carrier protein reductase I from Candidatus Liberibacter asiaticus.
Protein Sci., 23, 2014
4X1Q
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BU of 4x1q by Molmil
The crystal structure of mupain-1 in complex with murinised human uPA at pH7.4
分子名称: Urokinase-type plasminogen activator, mupain-1
著者Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M.
登録日2014-11-25
公開日2015-03-25
最終更新日2015-11-04
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility.
Plos One, 9, 2014
4X0W
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BU of 4x0w by Molmil
The crystal structure of mupain-1-17 in complex with murinised human uPA
分子名称: SULFATE ION, Urokinase-type plasminogen activator, mupain-1-17, ...
著者Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M.
登録日2014-11-24
公開日2015-10-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues.
Int.J.Biochem.Cell Biol., 62, 2015
4X1P
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BU of 4x1p by Molmil
The crystal structure of mupain-1-17 in complex with murinised human uPA at pH4.6
分子名称: MUPAIN-1-17, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M.
登録日2014-11-25
公開日2015-10-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues.
Int.J.Biochem.Cell Biol., 62, 2015
4X1S
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BU of 4x1s by Molmil
The crystal structure of mupain-1-16-D9A in complex with murinised human uPA at pH7.4
分子名称: Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide
著者Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M.
登録日2014-11-25
公開日2015-10-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility.
Plos One, 9, 2014
4X1R
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BU of 4x1r by Molmil
The crystal structure of mupain-1-12 in complex with murinised human uPA at pH7.4
分子名称: 1-phenylguanidine, Urokinase-type plasminogen activator, mupain-1-12
著者Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M.
登録日2014-11-25
公開日2015-03-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility.
Plos One, 9, 2014
3MHW
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BU of 3mhw by Molmil
The complex crystal Structure of Urokianse and 2-Aminobenzothiazole
分子名称: 1,3-benzothiazol-2-amine, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.-G, Yuan, C, Chen, L.-Q, Huang, M.-D.
登録日2010-04-09
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structures of 2-Aminobenzothiazole-based Inhibitors in Complexes with Urokinase-type Plasminogen Activator
CHIN.J.STRUCT.CHEM., 28, 2009
4DVA
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BU of 4dva by Molmil
The crystal structure of human urokinase-type plasminogen activator catalytic domain
分子名称: HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M.
登録日2012-02-23
公開日2013-01-16
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
3M61
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BU of 3m61 by Molmil
Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
分子名称: Urokinase-type plasminogen activator, upain-1 W3A
著者Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M.
登録日2010-03-15
公開日2010-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition
TO BE PUBLISHED
8IN0
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BU of 8in0 by Molmil
Structure of the Keap1 Kelch domain in complex with PGAM5-derived peptide
分子名称: Kelch-like ECH-associated protein 1, PGAM5 12-mer peptide, SULFATE ION
著者Jiang, L, Wang, C.
登録日2023-03-08
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the Keap1 Kelch domain in complex with PGAM5-derived peptide
To Be Published

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