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2N3X

Solution Structure of TDP-43 Amyloidogenic Core Region

Summary for 2N3X
Entry DOI10.2210/pdb2n3x/pdb
NMR InformationBMRB: 25659
DescriptorTAR DNA-binding protein 43 (1 entity in total)
Functional Keywordstdp-43, amyloidogenic core region, dna binding protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus : Q13148
Total number of polymer chains1
Total formula weight5207.80
Authors
Jiang, L.,Zhao, J.,Zhou, C.,Hu, H. (deposition date: 2015-06-11, release date: 2016-04-20, Last modification date: 2024-05-15)
Primary citationJiang, L.L.,Zhao, J.,Yin, X.F.,He, W.T.,Yang, H.,Che, M.X.,Hu, H.Y.
Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation
Sci Rep, 6:23928-23928, 2016
Cited by
PubMed: 27030292
DOI: 10.1038/srep23928
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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