4CMQ
| Crystal structure of Mn-bound S.pyogenes Cas9 | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | 登録日 | 2014-01-17 | 公開日 | 2014-02-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation Science, 343, 2014
|
|
2VXG
| Crystal structure of the conserved C-terminal region of Ge-1 | 分子名称: | CG6181-PA, ISOFORM A | 著者 | Jinek, M, Eulalio, A, Lingel, A, Helms, S, Conti, E, Izaurralde, E. | 登録日 | 2008-07-04 | 公開日 | 2008-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The C-Terminal Region of Ge-1 Presents Conserved Structural Features Required for P-Body Localization. RNA, 14, 2008
|
|
2J0B
| Structure of the catalytic domain of mouse Manic Fringe in complex with UDP and manganese | 分子名称: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, MANGANESE (II) ION, POTASSIUM ION, ... | 著者 | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | 登録日 | 2006-08-01 | 公開日 | 2006-09-04 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe Nat.Struct.Mol.Biol., 13, 2006
|
|
2J0A
| Structure of the catalytic domain of mouse Manic Fringe | 分子名称: | BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, POTASSIUM ION, SULFATE ION | 著者 | Jinek, M, Chen, Y.-W, Clausen, H, Cohen, S.M, Conti, E. | 登録日 | 2006-08-01 | 公開日 | 2006-09-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe Nat.Struct.Mol.Biol., 13, 2006
|
|
1W3B
| The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | 分子名称: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | 著者 | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | 登録日 | 2004-07-14 | 公開日 | 2004-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha Nat.Struct.Mol.Biol., 11, 2004
|
|
6FDL
| |
6F9S
| |
4CMP
| Crystal structure of S. pyogenes Cas9 | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | 登録日 | 2014-01-16 | 公開日 | 2014-02-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation. Science, 343, 2014
|
|
6I1L
| |
6I1K
| |
2X04
| Crystal structure of the PABC-TNRC6C complex | 分子名称: | POLYADENYLATE-BINDING PROTEIN 1, SULFATE ION, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN | 著者 | Jinek, M, Fabian, M.R, Coyle, S.M, Sonenberg, N, Doudna, J.A. | 登録日 | 2009-12-04 | 公開日 | 2010-01-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation Nat.Struct.Mol.Biol., 17, 2010
|
|
4C98
| |
2Y35
| |
4C9D
| |
4C8Z
| Cas6 (TTHA0078) product complex | 分子名称: | CAS6A, POTASSIUM ION, R1 REPEAT RNA CLEAVAGE PRODUCT, ... | 著者 | Jinek, M, Niewoehner, O, Doudna, J.A. | 登録日 | 2013-10-02 | 公開日 | 2013-11-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases. Nucleic Acids Res., 42, 2014
|
|
4C8Y
| |
4C97
| |
9EZX
| Vibrio cholerae DdmD apo complex | 分子名称: | Helicase/UvrB N-terminal domain-containing protein | 著者 | Loeff, L, Jinek, M. | 登録日 | 2024-04-14 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Molecular mechanism of plasmid elimination by the DdmDE defense system. Science, 385, 2024
|
|
9EZY
| Vibrio cholerae DdmD-DdmE holo complex | 分子名称: | 14 nucleotide DNA guide with terminal 5' phosphate, Helicase/UvrB N-terminal domain-containing protein, MAGNESIUM ION, ... | 著者 | Loeff, L, Jinek, M. | 登録日 | 2024-04-14 | 公開日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Molecular mechanism of plasmid elimination by the DdmDE defense system. Science, 385, 2024
|
|
6O16
| Crystal structure of murine DHX37 in complex with RNA | 分子名称: | DEAH (Asp-Glu-Ala-His) box polypeptide 37, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3') | 著者 | Boneberg, F, Brandmann, T, Kobel, L, van den Heuvel, J, Bargsten, K, Bammert, L, Kutay, U, Jinek, M. | 登録日 | 2019-02-18 | 公開日 | 2019-04-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.875 Å) | 主引用文献 | Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis. Rna, 25, 2019
|
|
6TUG
| |
5AF2
| |
5NFV
| Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ... | 著者 | Swarts, D.C, van der Oost, J, Jinek, M. | 登録日 | 2017-03-16 | 公開日 | 2017-06-14 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a. Mol. Cell, 66, 2017
|
|
5NG6
| |
5L6E
| |