5NG6
Crystal structure of FnCas12a bound to a crRNA
Summary for 5NG6
Entry DOI | 10.2210/pdb5ng6/pdb |
Descriptor | CRISPR-associated endonuclease Cpf1, crRNA, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | crispr, cas, cpf1, cas12a, nuclease, genome editing, r-loop, crrna, ruvc, hydrolase |
Biological source | Francisella tularensis subsp. novicida (strain U112) More |
Total number of polymer chains | 8 |
Total formula weight | 664171.48 |
Authors | Swarts, D.C.,van der Oost, J.,Jinek, M. (deposition date: 2017-03-16, release date: 2017-06-14, Last modification date: 2024-01-17) |
Primary citation | Swarts, D.C.,van der Oost, J.,Jinek, M. Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a. Mol. Cell, 66:221-233.e4, 2017 Cited by PubMed: 28431230DOI: 10.1016/j.molcel.2017.03.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.342 Å) |
Structure validation
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