5NG6
Crystal structure of FnCas12a bound to a crRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | CRISPR-associated endonuclease Cpf1 | polymer | 1302 | 152282.2 | 4 | UniProt (A0Q7Q2) Pfam (PF18501) Pfam (PF21918) Pfam (PF22222) Pfam (PF18516) Pfam (PF18510) | Francisella tularensis subsp. novicida (strain U112) | FnCpf1 |
| 2 | B, D, F, H (B, D, F, H) | crRNA | polymer | 43 | 13712.1 | 4 | synthetic construct | ||
| 3 | I, J, K, L, M... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | Q, R, S, T, U... (A, B, D, E, F...) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 2 - 1300 (UniProt: A0Q7Q2)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Asn 0 | - | expression tag |
| Ala 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 663977.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 194.4 | |
| All* | Total formula weight | 664171.5 |
