2Y35

Crystal structure of Xrn1-substrate complex

Summary for 2Y35

• Entry DOI: 10.2210/pdb2y35/pdb
• Descriptor: LD22664P, DT11 (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: hydrolase-dna complex, rna degradation, exonuclease 5'-3', rna interference, hydrolase/dna
• Biological source: DROSOPHILA MELANOGASTER (FRUIT FLY); More
• Total number of polymer chains: 2
• Total formula weight: 135721.44

Authors

Jinek, M.,Coyle, S.M.,Doudna, J.A. (deposition date: 2010-12-18, release date: 2011-03-16, Last modification date: 2011-08-03)

• Primary citation: Jinek, M.,Coyle, S.M.,Doudna, J.A.; Coupled 5' Nucleotide Recognition and Processivity in Xrn1-Mediated Mrna Decay.; Mol.Cell, 41:600-, 2011; PubMed: 21362555; DOI: 10.1016/J.MOLCEL.2011.02.004

Experimental method

X-RAY DIFFRACTION (3.2 Å)