6TUG
Enterococcus italicus Csm6 bound to cyclic hexa-2'-fluoro-hexa-dAMP
Summary for 6TUG
Entry DOI | 10.2210/pdb6tug/pdb |
Descriptor | CRISPR system endoribonuclease Csm6, 2'-deoxy-2'-fluoroadenosine 5'-(dihydrogen phosphate), SULFATE ION, ... (4 entities in total) |
Functional Keywords | crispr, cyclic oligoadenylate, rnase, nuclease, rna binding protein |
Biological source | Enterococcus italicus (strain DSM 15952 / LMG 22039 / TP 1.5) |
Total number of polymer chains | 8 |
Total formula weight | 416501.47 |
Authors | Garcia-Doval, C.,Jinek, M. (deposition date: 2020-01-07, release date: 2020-02-26, Last modification date: 2024-05-15) |
Primary citation | Garcia-Doval, C.,Schwede, F.,Berk, C.,Rostol, J.T.,Niewoehner, O.,Tejero, O.,Hall, J.,Marraffini, L.A.,Jinek, M. Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6. Nat Commun, 11:1596-1596, 2020 Cited by PubMed: 32221291DOI: 10.1038/s41467-020-15334-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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