6TUG
Enterococcus italicus Csm6 bound to cyclic hexa-2'-fluoro-hexa-dAMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0051607 | biological_process | defense response to virus |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0051607 | biological_process | defense response to virus |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0051607 | biological_process | defense response to virus |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0051607 | biological_process | defense response to virus |
| E | 0004519 | molecular_function | endonuclease activity |
| E | 0051607 | biological_process | defense response to virus |
| F | 0004519 | molecular_function | endonuclease activity |
| F | 0051607 | biological_process | defense response to virus |
| G | 0004519 | molecular_function | endonuclease activity |
| G | 0051607 | biological_process | defense response to virus |
| H | 0004519 | molecular_function | endonuclease activity |
| H | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| A | ARG274 |
| A | ARG372 |
| B | ARG372 |
| B | HIS377 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 504 |
| Chain | Residue |
| C | ARG372 |
| C | HIS377 |
| D | ARG372 |
| D | HIS377 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 504 |
| Chain | Residue |
| F | ARG372 |
| F | HIS377 |
| E | ARG372 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 504 |
| Chain | Residue |
| G | ARG372 |
| G | HIS377 |
| H | HIS377 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for residues AF2 A 501 and AF2 A 503 |
| Chain | Residue |
| A | GLY9 |
| A | ASN10 |
| A | THR11 |
| A | ARG15 |
| A | ARG18 |
| A | ASP19 |
| A | THR39 |
| A | SER41 |
| A | ILE42 |
| A | GLU80 |
| A | THR111 |
| A | GLY113 |
| A | THR114 |
| A | THR139 |
| A | PRO140 |
| A | ARG173 |
| A | AF2502 |
| B | AF2501 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residues AF2 A 501 and AF2 B 501 |
| Chain | Residue |
| A | GLY9 |
| A | ASN10 |
| A | THR11 |
| A | ARG15 |
| A | ARG18 |
| A | ASP19 |
| A | THR111 |
| A | THR139 |
| A | PRO140 |
| A | ARG173 |
| A | AF2503 |
| B | GLU80 |
| B | ASN81 |
| B | PRO115 |
| B | GLN116 |
| B | AF2502 |
| site_id | AC7 |
| Number of Residues | 30 |
| Details | binding site for residues AF2 A 502 and AF2 B 503 |
| Chain | Residue |
| A | ASN10 |
| A | THR39 |
| A | SER41 |
| A | ILE42 |
| A | GLU80 |
| A | ASN81 |
| A | GLY113 |
| A | THR114 |
| A | PRO115 |
| A | GLN116 |
| A | AF2501 |
| B | ILE8 |
| B | GLY9 |
| B | ASN10 |
| B | THR11 |
| B | ARG15 |
| B | ASP19 |
| B | THR39 |
| B | SER41 |
| B | GLU80 |
| B | THR111 |
| B | GLY113 |
| B | THR114 |
| B | MET117 |
| B | GLU118 |
| B | THR139 |
| B | PRO140 |
| B | ARG173 |
| B | AF2501 |
| B | HOH629 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residues AF2 A 502 and AF2 A 503 |
| Chain | Residue |
| A | ASN10 |
| A | THR39 |
| A | SER41 |
| A | ILE42 |
| A | GLU80 |
| A | ASN81 |
| A | GLY113 |
| A | THR114 |
| A | PRO115 |
| A | GLN116 |
| A | AF2501 |
| B | GLU118 |
| B | THR139 |
| B | AF2503 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | binding site for residues AF2 B 501 and AF2 B 502 |
| Chain | Residue |
| B | ASN81 |
| B | GLY113 |
| B | THR114 |
| B | PRO115 |
| B | GLN116 |
| B | MET117 |
| B | AF2503 |
| A | THR139 |
| A | AF2501 |
| B | ILE8 |
| B | ASN10 |
| B | THR39 |
| B | SER41 |
| B | GLU80 |
| site_id | AD1 |
| Number of Residues | 19 |
| Details | binding site for residues AF2 B 502 and AF2 B 503 |
| Chain | Residue |
| A | AF2502 |
| B | ILE8 |
| B | GLY9 |
| B | ASN10 |
| B | THR11 |
| B | ARG15 |
| B | ASP19 |
| B | THR39 |
| B | SER41 |
| B | GLU80 |
| B | THR111 |
| B | GLY113 |
| B | THR114 |
| B | MET117 |
| B | THR139 |
| B | PRO140 |
| B | ARG173 |
| B | AF2501 |
| B | HOH629 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residues AF2 C 501 and AF2 C 503 |
| Chain | Residue |
| C | GLY9 |
| C | ASN10 |
| C | THR11 |
| C | ARG15 |
| C | ASP19 |
| C | THR39 |
| C | SER41 |
| C | GLU80 |
| C | THR111 |
| C | GLY113 |
| C | THR114 |
| C | THR139 |
| C | PRO140 |
| C | ARG173 |
| C | AF2502 |
| D | AF2501 |
| site_id | AD3 |
| Number of Residues | 18 |
| Details | binding site for residues AF2 C 501 and AF2 D 501 |
| Chain | Residue |
| C | GLY9 |
| C | ASN10 |
| C | THR11 |
| C | ARG15 |
| C | ASP19 |
| C | THR111 |
| C | GLU118 |
| C | THR139 |
| C | PRO140 |
| C | LEU141 |
| C | ARG173 |
| C | AF2503 |
| D | GLU80 |
| D | ASN81 |
| D | THR114 |
| D | PRO115 |
| D | GLN116 |
| D | AF2502 |
| site_id | AD4 |
| Number of Residues | 31 |
| Details | binding site for residues AF2 C 502 and AF2 D 503 |
| Chain | Residue |
| C | ASN10 |
| C | THR39 |
| C | SER41 |
| C | VAL79 |
| C | GLU80 |
| C | ASN81 |
| C | GLY113 |
| C | THR114 |
| C | PRO115 |
| C | GLN116 |
| C | AF2501 |
| C | HOH616 |
| D | ILE8 |
| D | ASN10 |
| D | THR11 |
| D | ARG15 |
| D | ARG18 |
| D | THR39 |
| D | SER41 |
| D | ILE42 |
| D | GLU80 |
| D | THR111 |
| D | GLY113 |
| D | THR114 |
| D | GLU118 |
| D | VAL137 |
| D | THR139 |
| D | PRO140 |
| D | ARG173 |
| D | AF2501 |
| D | HOH631 |
| site_id | AD5 |
| Number of Residues | 14 |
| Details | binding site for residues AF2 C 502 and AF2 C 503 |
| Chain | Residue |
| C | ASN10 |
| C | THR39 |
| C | SER41 |
| C | VAL79 |
| C | GLU80 |
| C | ASN81 |
| C | GLY113 |
| C | THR114 |
| C | PRO115 |
| C | GLN116 |
| C | AF2501 |
| C | HOH616 |
| D | GLU118 |
| D | AF2503 |
| site_id | AD6 |
| Number of Residues | 17 |
| Details | binding site for residues AF2 D 501 and AF2 D 502 |
| Chain | Residue |
| C | GLU118 |
| C | THR139 |
| C | LEU141 |
| C | AF2501 |
| D | ILE8 |
| D | ASN10 |
| D | THR39 |
| D | SER41 |
| D | ILE42 |
| D | GLU80 |
| D | ASN81 |
| D | GLY113 |
| D | THR114 |
| D | PRO115 |
| D | GLN116 |
| D | AF2503 |
| D | HOH631 |
| site_id | AD7 |
| Number of Residues | 19 |
| Details | binding site for residues AF2 D 502 and AF2 D 503 |
| Chain | Residue |
| C | AF2502 |
| D | ILE8 |
| D | ASN10 |
| D | THR11 |
| D | ARG15 |
| D | ARG18 |
| D | THR39 |
| D | SER41 |
| D | ILE42 |
| D | GLU80 |
| D | THR111 |
| D | GLY113 |
| D | THR114 |
| D | VAL137 |
| D | THR139 |
| D | PRO140 |
| D | ARG173 |
| D | AF2501 |
| D | HOH631 |
| site_id | AD8 |
| Number of Residues | 17 |
| Details | binding site for residues AF2 E 501 and AF2 F 501 |
| Chain | Residue |
| E | ASN10 |
| E | THR11 |
| E | ARG15 |
| E | ASP19 |
| E | THR111 |
| E | GLU118 |
| E | VAL137 |
| E | THR139 |
| E | PRO140 |
| E | ARG173 |
| E | AF2503 |
| F | GLU80 |
| F | ASN81 |
| F | PRO115 |
| F | GLN116 |
| F | AF2502 |
| F | HOH618 |
| site_id | AD9 |
| Number of Residues | 16 |
| Details | binding site for residues AF2 E 501 and AF2 E 503 |
| Chain | Residue |
| E | ASN10 |
| E | THR11 |
| E | ARG15 |
| E | ASP19 |
| E | THR39 |
| E | SER41 |
| E | GLU80 |
| E | THR111 |
| E | GLY113 |
| E | THR114 |
| E | VAL137 |
| E | THR139 |
| E | PRO140 |
| E | ARG173 |
| E | AF2502 |
| F | AF2501 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for residues AF2 E 502 and AF2 E 503 |
| Chain | Residue |
| E | ASN10 |
| E | THR39 |
| E | SER41 |
| E | GLU80 |
| E | ASN81 |
| E | GLY113 |
| E | THR114 |
| E | PRO115 |
| E | GLN116 |
| E | AF2501 |
| F | GLU118 |
| F | THR139 |
| F | AF2503 |
| site_id | AE2 |
| Number of Residues | 32 |
| Details | binding site for residues AF2 E 502 and AF2 F 503 |
| Chain | Residue |
| E | ASN10 |
| E | THR39 |
| E | SER41 |
| E | GLU80 |
| E | ASN81 |
| E | GLY113 |
| E | THR114 |
| E | PRO115 |
| E | GLN116 |
| E | AF2501 |
| F | ILE8 |
| F | ASN10 |
| F | THR11 |
| F | ARG15 |
| F | ARG18 |
| F | ASP19 |
| F | THR39 |
| F | SER41 |
| F | ILE42 |
| F | GLU80 |
| F | THR111 |
| F | GLY113 |
| F | THR114 |
| F | GLU118 |
| F | VAL137 |
| F | SER138 |
| F | THR139 |
| F | PRO140 |
| F | ARG173 |
| F | AF2501 |
| F | HOH628 |
| F | HOH634 |
| site_id | AE3 |
| Number of Residues | 15 |
| Details | binding site for residues AF2 F 501 and AF2 F 502 |
| Chain | Residue |
| E | GLU118 |
| E | AF2501 |
| F | ILE8 |
| F | ASN10 |
| F | THR39 |
| F | SER41 |
| F | ILE42 |
| F | GLU80 |
| F | ASN81 |
| F | GLY113 |
| F | THR114 |
| F | PRO115 |
| F | GLN116 |
| F | AF2503 |
| F | HOH618 |
| site_id | AE4 |
| Number of Residues | 22 |
| Details | binding site for residues AF2 F 502 and AF2 F 503 |
| Chain | Residue |
| E | AF2502 |
| F | ILE8 |
| F | ASN10 |
| F | THR11 |
| F | ARG15 |
| F | ARG18 |
| F | ASP19 |
| F | THR39 |
| F | SER41 |
| F | ILE42 |
| F | GLU80 |
| F | THR111 |
| F | GLY113 |
| F | THR114 |
| F | VAL137 |
| F | SER138 |
| F | THR139 |
| F | PRO140 |
| F | ARG173 |
| F | AF2501 |
| F | HOH628 |
| F | HOH634 |
| site_id | AE5 |
| Number of Residues | 17 |
| Details | binding site for residues AF2 G 501 and AF2 H 501 |
| Chain | Residue |
| G | GLY9 |
| G | ASN10 |
| G | THR11 |
| G | ARG15 |
| G | ASP19 |
| G | THR111 |
| G | GLU118 |
| G | THR139 |
| G | PRO140 |
| G | ARG173 |
| G | AF2503 |
| H | GLU80 |
| H | ASN81 |
| H | THR114 |
| H | PRO115 |
| H | GLN116 |
| H | AF2502 |
| site_id | AE6 |
| Number of Residues | 17 |
| Details | binding site for residues AF2 G 501 and AF2 G 503 |
| Chain | Residue |
| G | ILE8 |
| G | GLY9 |
| G | ASN10 |
| G | THR11 |
| G | ARG15 |
| G | ASP19 |
| G | THR39 |
| G | SER41 |
| G | ILE42 |
| G | THR111 |
| G | GLY113 |
| G | THR114 |
| G | THR139 |
| G | PRO140 |
| G | ARG173 |
| G | AF2502 |
| H | AF2501 |
| site_id | AE7 |
| Number of Residues | 17 |
| Details | binding site for residues AF2 G 502 and AF2 G 503 |
| Chain | Residue |
| G | ILE8 |
| G | ASN10 |
| G | THR39 |
| G | SER41 |
| G | ILE42 |
| G | VAL79 |
| G | GLU80 |
| G | ASN81 |
| G | GLY113 |
| G | THR114 |
| G | PRO115 |
| G | GLN116 |
| G | AF2501 |
| G | HOH610 |
| G | HOH615 |
| H | GLU118 |
| H | AF2503 |
| site_id | AE8 |
| Number of Residues | 33 |
| Details | binding site for residues AF2 G 502 and AF2 H 503 |
| Chain | Residue |
| G | ILE8 |
| G | ASN10 |
| G | THR39 |
| G | SER41 |
| G | ILE42 |
| G | VAL79 |
| G | GLU80 |
| G | ASN81 |
| G | GLY113 |
| G | THR114 |
| G | PRO115 |
| G | GLN116 |
| G | AF2501 |
| G | HOH610 |
| G | HOH615 |
| H | ILE8 |
| H | ASN10 |
| H | THR11 |
| H | ARG15 |
| H | ASP19 |
| H | THR39 |
| H | SER41 |
| H | GLU80 |
| H | THR111 |
| H | GLY113 |
| H | THR114 |
| H | GLU118 |
| H | VAL137 |
| H | THR139 |
| H | PRO140 |
| H | ARG173 |
| H | AF2501 |
| H | HOH623 |
| site_id | AE9 |
| Number of Residues | 15 |
| Details | binding site for residues AF2 H 501 and AF2 H 502 |
| Chain | Residue |
| G | GLU118 |
| G | THR139 |
| G | AF2501 |
| H | ILE8 |
| H | ASN10 |
| H | THR39 |
| H | SER41 |
| H | GLU80 |
| H | ASN81 |
| H | GLY113 |
| H | THR114 |
| H | PRO115 |
| H | GLN116 |
| H | AF2503 |
| H | HOH623 |
| site_id | AF1 |
| Number of Residues | 19 |
| Details | binding site for residues AF2 H 502 and AF2 H 503 |
| Chain | Residue |
| G | AF2502 |
| G | HOH610 |
| H | ILE8 |
| H | ASN10 |
| H | THR11 |
| H | ARG15 |
| H | ASP19 |
| H | THR39 |
| H | SER41 |
| H | GLU80 |
| H | THR111 |
| H | GLY113 |
| H | THR114 |
| H | VAL137 |
| H | THR139 |
| H | PRO140 |
| H | ARG173 |
| H | AF2501 |
| H | HOH623 |
