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PDB: 2898 件

3PXM
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Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix
分子名称: Monellin chain B/Monellin chain A chimeric protein
著者Hobbs, J.R, Templeton, C.M, Pour, S.O, Blanch, E.W, Munger, S.M, Conn, G.L.
登録日2010-12-10
公開日2011-04-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
3PYJ
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Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix
分子名称: FORMIC ACID, Monellin chain B/Monellin chain A chimeric protein
著者Hobbs, J.R, Conn, G.C, Munger, S.D, Templeton, C.M.
登録日2010-12-13
公開日2011-04-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
1S3Y
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Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry
分子名称: 6-(OCTAHYDRO-1H-INDOL-1-YLMETHYL)DECAHYDROQUINAZOLINE-2,4-DIAMINE, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V, Luft, J.R, Pangborn, W, Gangjee, A, Queener, S.F.
登録日2004-01-14
公開日2004-03-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry.
Acta Crystallogr.,Sect.D, 60, 2004
5JJW
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Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain
分子名称: 1,2-ETHANEDIOL, Squamous cell carcinoma antigen recognized by T-cells 3, UNKNOWN ATOM OR ION, ...
著者Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2016-04-25
公開日2016-05-04
最終更新日2016-07-06
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Crystal structure of the HAT domain of sart3 in complex with USP15 DUSP-UBL domain
to be published
1TSH
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TERTIARY STRUCTURES OF THREE AMYLOIDOGENIC TRANSTHYRETIN VARIANTS AND IMPLICATIONS FOR AMYLOID FIBRIL FORMATION
分子名称: TRANSTHYRETIN
著者Schormann, N, Murrell, J.R, Benson, M.D.
登録日1996-10-16
公開日1997-04-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation.
Amyloid, 5, 1998
1TPH
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1.8 ANGSTROMS CRYSTAL STRUCTURE OF WILD TYPE CHICKEN TRIOSEPHOSPHATE ISOMERASE-PHOSPHOGLYCOLOHYDROXAMATE COMPLEX
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1993-12-22
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution.
Biochemistry, 33, 1994
5K6G
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Crystal structure of prefusion-stabilized RSV F single-chain 9-24 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0
著者Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K7L
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Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calmodulin, ...
著者Whicher, J.R, MacKinnon, R.
登録日2016-05-26
公開日2016-08-17
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism.
Science, 353, 2016
5JR1
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Crystal structure of 10E8 gHV-matureL antigen-binding fragment.
分子名称: 10E8 heavy chain, 10E8 mature light chain, ZINC ION
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-05
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
6N92
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Methylmalonyl-CoA decarboxylase in complex with 2-nitronate-propionyl-CoA
分子名称: (2E)-2-(hydroxyimino)propanoic acid, IMIDAZOLE, Methylmalonyl-CoA decarboxylase, ...
著者Stunkard, L.M, Dixon, A.D, Huth, T.J, Lohman, J.R.
登録日2018-11-30
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Sulfonate/Nitro Bearing Methylmalonyl-Thioester Isosteres Applied to Methylmalonyl-CoA Decarboxylase Structure-Function Studies.
J. Am. Chem. Soc., 141, 2019
3RF2
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BU of 3rf2 by Molmil
Crystal Structure of 30S Ribosomal Protein S8 from Aquifex Aeolicus
分子名称: 30S ribosomal protein S8, SULFATE ION
著者Menichelli, E, Williamson, J.R.
登録日2011-04-05
公開日2011-11-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The Structure of Aquifex aeolicus Ribosomal Protein S8 Reveals a Unique Subdomain that Contributes to an Extremely Tight Association with 16S rRNA.
J.Mol.Biol., 415, 2012
6N97
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Methylmalonyl-CoA decarboxylase in complex with 2-sulfonate-propionyl-amino(dethia)-CoA
分子名称: (2R)-sulfonatepropionyl-amino(dethia)-CoA, (2S)-sulfonatepropionyl-amino(dethia)-CoA, IMIDAZOLE, ...
著者Stunkard, L.M, Dixon, A.D, Huth, T.J, Lohman, J.R.
登録日2018-11-30
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Sulfonate/Nitro Bearing Methylmalonyl-Thioester Isosteres Applied to Methylmalonyl-CoA Decarboxylase Structure-Function Studies.
J. Am. Chem. Soc., 141, 2019
1R57
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NMR Solution Structure of a GCN5-like putative N-acetyltransferase from Staphylococcus aureus. Northeast Structural Genomics Consortium Target ZR31
分子名称: conserved hypothetical protein
著者Cort, J.R, Acton, T.B, Ma, L, Xiao, R.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2003-10-09
公開日2004-03-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins.
J.STRUCT.FUNCT.GENOM., 9, 2008
6MM4
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BU of 6mm4 by Molmil
Solution NMR Structure of Engineered Cystine Knot Protein 2.5F
分子名称: Engineered Cystine Knot Protein 2.5F
著者Cochran, F.V, Cochran, J.R.
登録日2018-09-29
公開日2019-10-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Engineered Cystine Knot Protein 2.5F
To be published
3ROL
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BU of 3rol by Molmil
Murine class I major histocompatibility complex H-2Kb in complex with post-translationally modified LCMV-derived gp34-41 peptide, comprising a nitrotyrosine at position 3
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Madhurantakam, C, Duru, A.D, Leong, C, Sandalova, T, Webb, J.R, Achour, A.
登録日2011-04-26
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nitro-tyrosination of the immunodominant LCMV epitope gp34-41 alters both its capacity to stabilize H-2Kb and the molecular surface of the MHC complex, affecting TCR recognition
PLoS ONE, 2012
5K6C
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BU of 5k6c by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0, SULFATE ION
著者Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-10-12
最終更新日2016-10-19
実験手法X-RAY DIFFRACTION (3.576 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
3R2D
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BU of 3r2d by Molmil
Crystal Structure of Antitermination Factors NusB and NusE in complex with dsRNA
分子名称: 30S ribosomal protein S10, 5'-R(*GP*GP*CP*UP*CP*CP*UP*UP*GP*GP*CP*A)-3', DI(HYDROXYETHYL)ETHER, ...
著者Stagno, J.R, Ji, X.
登録日2011-03-14
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献Structural basis for RNA recognition by NusB and NusE in the initiation of transcription antitermination.
Nucleic Acids Res., 39, 2011
1R8W
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Native structure of the B12-independent glycerol dehydratase from clostridium butyricum
分子名称: glycerol dehydratase
著者Lanzilotta, W.N, Soucaille, P, O'Brien, J.R, Raynaud, C.
登録日2003-10-28
公開日2004-06-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization.
Biochemistry, 43, 2004
3RPX
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Crystal structure of complement component 1, q subcomponent binding protein, C1QBP
分子名称: Complement component 1 Q subcomponent-binding protein, UNKNOWN ATOM OR ION
著者Tempel, W, Tong, Y, Crombet, L, Shen, Y, Guan, X, Nedyalkova, L, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
登録日2011-04-27
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of complement component 1, q subcomponent binding protein, C1QBP
to be published
1R9D
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Glycerol bound form of the B12-independent glycerol dehydratase from Clostridium butyricum
分子名称: GLYCEROL, glycerol dehydratase
著者Lanzilotta, W.N, O'Brien, J.R, Raynaud, C, Soucaille, P.
登録日2003-10-28
公開日2004-06-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization.
Biochemistry, 43, 2004
1RGZ
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Enterobacter cloacae GC1 Class C beta-Lactamase Complexed with Transition-State Analog of Cefotaxime
分子名称: GLYCEROL, class C beta-lactamase, {[(2E)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ETHANOYL]AMINO}METHYLPHOSPHONIC ACID
著者Nukaga, M, Kumar, S, Nukaga, K, Pratt, R.F, Knox, J.R.
登録日2003-11-13
公開日2004-04-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Hydrolysis of third-generation cephalosporins by class C beta-lactamases. Structures of a transition state analog of cefotoxamine in wild-type and extended spectrum enzymes.
J.Biol.Chem., 279, 2004
6O1S
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Structure of human plasma kallikrein protease domain with inhibitor
分子名称: 1,2-ETHANEDIOL, N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-1-({4-[(1H-pyrazol-1-yl)methyl]phenyl}methyl)-1H-pyrazole-4-carboxamide, PHOSPHATE ION, ...
著者Partridge, J.R, Choy, R.M.
登録日2019-02-21
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition.
J.Struct.Biol., 206, 2019
5K4L
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Crystal structure of KDM5A in complex with a naphthyridone inhibitor
分子名称: Lysine-specific demethylase 5A, NICKEL (II) ION, Unknown Peptide, ...
著者Kiefer, J.R, Vinogradova, M.V.
登録日2016-05-20
公開日2016-08-10
最終更新日2016-09-07
実験手法X-RAY DIFFRACTION (3.179 Å)
主引用文献Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
3SCS
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BU of 3scs by Molmil
Crystal Structure of Rice BGlu1 E386S Mutant Complexed with alpha-Glucosyl Fluoride
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, GLYCEROL, ...
著者Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R.
登録日2011-06-08
公開日2012-06-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases
to be published
3SE6
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Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Birtley, J.R, Saridakis, E, Stratikos, E, Mavridis, I.M.
登録日2011-06-10
公開日2011-12-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing.
Biochemistry, 51, 2012

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件を2024-09-04に公開中

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