3SE6

Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2

Summary for 3SE6

• Entry DOI: 10.2210/pdb3se6/pdb
• Descriptor: Endoplasmic reticulum aminopeptidase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: thermolysin-like catalytic domain, aminopeptidase, zinc binding, glycosylation, endoplasmic reticulum, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 226107.54

Authors

Birtley, J.R.,Saridakis, E.,Stratikos, E.,Mavridis, I.M. (deposition date: 2011-06-10, release date: 2011-12-21, Last modification date: 2020-07-29)

• Primary citation: Birtley, J.R.,Saridakis, E.,Stratikos, E.,Mavridis, I.M.; The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing.; Biochemistry, 51:286-295, 2012; PubMed: 22106953; DOI: 10.1021/bi201230p

Experimental method

X-RAY DIFFRACTION (3.08 Å)