3ROL

Murine class I major histocompatibility complex H-2Kb in complex with post-translationally modified LCMV-derived gp34-41 peptide, comprising a nitrotyrosine at position 3

Summary for 3ROL

• Entry DOI: 10.2210/pdb3rol/pdb
• Related: 1S7Q 3ROO
• Descriptor: H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Pre-glycoprotein polyprotein GP complex, ... (7 entities in total)
• Functional Keywords: t-cell receptor, mhc, gp34, ny-gp34, epitope, post-translational modification, lcmv, mhc class i, immune escape, immune system, t cell recognition, autoimmunity, t cell receptor, nitro-tyrosine, cell surface
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01901; Secreted: P01887
• Total number of polymer chains: 6
• Total formula weight: 89285.90

Authors

Madhurantakam, C.,Duru, A.D.,Leong, C.,Sandalova, T.,Webb, J.R.,Achour, A. (deposition date: 2011-04-26, release date: 2012-04-04, Last modification date: 2023-09-13)

• Primary citation: Madhurantakam, C.,Duru, A.D.,Leong, C.,Sandalova, T.,Webb, J.R.,Achour, A.; Nitro-tyrosination of the immunodominant LCMV epitope gp34-41 alters both its capacity to stabilize H-2Kb and the molecular surface of the MHC complex, affecting TCR recognition; PLoS ONE, 2012

Experimental method

X-RAY DIFFRACTION (2.6 Å)