3N05
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![BU of 3n05 by Molmil](/molmil-images/mine/3n05) | CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM STREPTOMYCES AVERMITILIS | Descriptor: | NH(3)-dependent NAD(+) synthetase, SULFATE ION | Authors: | Patskovsky, Y, Toro, R, Freeman, J, Do, J, Sauder, J.M, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-05-13 | Release date: | 2010-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Nh3-Dependent Nad+ Synthetase from Streptomyces Avermitilis To be Published
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1RSI
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![BU of 1rsi by Molmil](/molmil-images/mine/1rsi) | DHNA complex with 2-Amino-5-bromo-3-hydroxy-6-phenylpyrimidine | Descriptor: | 2-AMINO-5-BROMO-6-PHENYLPYRIMIDIN-4-OL, Dihydroneopterin aldolase | Authors: | Sanders, W.J, Nienaber, V.L, Lerner, C.G, McCall, J.O, Merrick, S.M, Swanson, S.J, Harlan, J.E, Stoll, V.S, Stamper, G.F, Betz, S.F, Condroski, K.R, Meadows, R.P, Severin, J.M, Walter, K.A, Magdalinos, P, Jakob, C.G, Wagner, R, Beutel, B.A. | Deposit date: | 2003-12-09 | Release date: | 2004-03-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization. J.Med.Chem., 47, 2004
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1LCS
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![BU of 1lcs by Molmil](/molmil-images/mine/1lcs) | RECEPTOR-BINDING DOMAIN FROM SUBGROUP B FELINE LEUKEMIA VIRUS | Descriptor: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Barnett, A.L, Wensel, D.L, Li, W, Fass, D, Cunningham, J.M. | Deposit date: | 2002-04-06 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Mechanism of a Coreceptor for Infection by a pathogenic feline retrovirus J.Virol., 77, 2003
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4CXA
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![BU of 4cxa by Molmil](/molmil-images/mine/4cxa) | Crystal structure of the human CDK12-cyclin K complex bound to AMPPNP | Descriptor: | CYCLIN-DEPENDENT KINASE 12, CYCLIN-K, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Dixon Clarke, S.E, Elkins, J.M, Pike, A.C.W, Nowak, R, Goubin, S, Mahajan, R.P, Kopec, J, Froese, S, Tallant, C, Carpenter, E.P, Mackenzie, A, Faust, B, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A.M, Bountra, C, Bullock, A. | Deposit date: | 2014-04-04 | Release date: | 2014-05-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structures of the Cdk12/Cyck Complex with AMP-Pnp Reveal a Flexible C-Terminal Kinase Extension Important for ATP Binding. Sci.Rep., 5, 2015
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2FEJ
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![BU of 2fej by Molmil](/molmil-images/mine/2fej) | Solution structure of human p53 DNA binding domain. | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Perez-Canadillas, J.M, Tidow, H, Freund, S.M, Rutherford, T.J, Ang, H.C, Fersht, A.R. | Deposit date: | 2005-12-16 | Release date: | 2006-01-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of p53 core domain: Structural basis for its instability Proc.Natl.Acad.Sci.Usa, 103, 2006
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3GM8
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![BU of 3gm8 by Molmil](/molmil-images/mine/3gm8) | Crystal structure of a beta-glycosidase from Bacteroides vulgatus | Descriptor: | GLYCEROL, Glycoside hydrolase family 2, candidate beta-glycosidase | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Iizuka, M, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-03-13 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a beta-glycosidase from Bacteroides vulgatus To be Published
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3BD8
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![BU of 3bd8 by Molmil](/molmil-images/mine/3bd8) | Glucogen Phosphorylase complex with 1(-D-glucopyranosyl) cytosine | Descriptor: | 4-amino-1-beta-D-glucopyranosylpyrimidin-2(1H)-one, Glycogen phosphorylase, muscle form, ... | Authors: | Sovantzis, D.A, Hadjiloi, T, Hayes, J.M, Zographos, S.E, Chrysina, E.D, Oikonomakos, N.G. | Deposit date: | 2007-11-14 | Release date: | 2008-11-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | D-Glucopyranosyl pyrimidine nucleoside binding to muscle glycogen phosphorylase b To be Published
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1R31
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![BU of 1r31 by Molmil](/molmil-images/mine/1r31) | HMG-CoA reductase from Pseudomonas mevalonii complexed with HMG-CoA | Descriptor: | (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, ... | Authors: | Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V. | Deposit date: | 2003-09-30 | Release date: | 2003-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase. To be Published
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3OEP
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![BU of 3oep by Molmil](/molmil-images/mine/3oep) | Crystal structure of TTHA0988 in space group P43212 | Descriptor: | GLYCEROL, Putative uncharacterized protein TTHA0988, SULFATE ION | Authors: | Jacques, D.A, Langley, D.B, Trewhella, J, Guss, J.M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2010-08-13 | Release date: | 2010-11-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase Acta Crystallogr.,Sect.D, 67, 2011
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1LK0
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![BU of 1lk0 by Molmil](/molmil-images/mine/1lk0) | Disulfide intermediate of C89L Arsenate reductase from pI258 | Descriptor: | CHLORIDE ION, POTASSIUM ION, arsenate reductase | Authors: | Messens, J, Martins, J.C, Van Belle, K, Brosens, E, Desmyter, A, De Gieter, M, Wieruszeski, J.M, Willem, R, Wyns, L, Zegers, I. | Deposit date: | 2002-04-23 | Release date: | 2002-08-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade. Proc.Natl.Acad.Sci.USA, 99, 2002
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1R65
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![BU of 1r65 by Molmil](/molmil-images/mine/1r65) | Crystal structure of ferrous soaked Ribonucleotide Reductase R2 subunit (wildtype) at pH 5 from E. coli | Descriptor: | FE (II) ION, MERCURY (II) ION, Ribonucleoside-diphosphate reductase 1 beta chain | Authors: | Voegtli, W.C, Sommerhalter, M, Saleh, L, Baldwin, J, Bollinger Jr, J.M, Rosenzweig, A.C. | Deposit date: | 2003-10-14 | Release date: | 2004-01-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Variable coordination geometries at the diiron(II) active site of ribonucleotide reductase R2. J.Am.Chem.Soc., 125, 2003
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3BHW
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![BU of 3bhw by Molmil](/molmil-images/mine/3bhw) | Crystal structure of an uncharacterized protein from Magnetospirillum magneticum | Descriptor: | Uncharacterized protein | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Lau, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-11-29 | Release date: | 2007-12-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of an uncharacterized protein from Magnetospirillum magneticum. To be Published
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3GP9
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![BU of 3gp9 by Molmil](/molmil-images/mine/3gp9) | Crystal structure of the Mimivirus NDK complexed with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside diphosphate kinase, ... | Authors: | Jeudy, S, Lartigue, A, Claverie, J.M, Abergel, C. | Deposit date: | 2009-03-23 | Release date: | 2009-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase. J.Virol., 83, 2009
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3BI9
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![BU of 3bi9 by Molmil](/molmil-images/mine/3bi9) | Tim-4 | Descriptor: | ACETATE ION, T-cell immunoglobulin and mucin domain-containing protein 4 | Authors: | Santiago, C, Ballesteros, A, Kaplan, G.G, Freeman, G.J, Casasnovas, J.M. | Deposit date: | 2007-11-30 | Release date: | 2008-01-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds. Immunity, 27, 2007
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4CKZ
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![BU of 4ckz by Molmil](/molmil-images/mine/4ckz) | Structure of the Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant | Descriptor: | 3-DEHYDROQUINATE DEHYDRATASE | Authors: | Otero, J.M, Llamas-Saiz, A.L, Maneiro, M, Peon, A, Sedes, A, Lamb, H, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | Deposit date: | 2014-01-10 | Release date: | 2015-03-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase To be Published
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3MFA
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![BU of 3mfa by Molmil](/molmil-images/mine/3mfa) | Computationally designed endo-1,4-beta-xylanase | Descriptor: | Endo-1,4-beta-xylanase, SULFATE ION | Authors: | Morin, A, Harp, J.M. | Deposit date: | 2010-04-01 | Release date: | 2010-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Computational design of an endo-1,4-{beta}-xylanase ligand binding site. Protein Eng.Des.Sel., 24, 2011
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1N7J
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![BU of 1n7j by Molmil](/molmil-images/mine/1n7j) | The structure of Phenylethanolamine N-methyltransferase in complex with S-adenosylhomocysteine and an iodinated inhibitor | Descriptor: | 7-IODO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | McMillan, F.M, Archbold, J, McLeish, M.J, Caine, J.M, Criscione, K.R, Grunewald, G.L, Martin, J.L. | Deposit date: | 2002-11-15 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase. J.Med.Chem., 47, 2004
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1N5Y
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![BU of 1n5y by Molmil](/molmil-images/mine/1n5y) | HIV-1 Reverse Transcriptase Crosslinked to Post-Translocation AZTMP-Terminated DNA (Complex P) | Descriptor: | 5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3', 5'-D(*AP*TP*GP*C*TP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ... | Authors: | Sarafianos, S.G, Clark Jr, A.D, Das, K, Tuske, S, Birktoft, J.J, Ilankumaran, P, Ramesha, A.R, Sayer, J.M, Jerina, D.M, Boyer, P.L, Hughes, S.H, Arnold, E. | Deposit date: | 2002-11-07 | Release date: | 2003-01-28 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of HIV-1 Reverse Transcriptase with Pre-Translocation and Post-Translocation AZTMP-Terminated DNA Embo J., 21, 2002
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1N9G
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![BU of 1n9g by Molmil](/molmil-images/mine/1n9g) | Mitochondrial 2-enoyl thioester reductase Etr1p/Etr2p heterodimer from Candida tropicalis | Descriptor: | 2,4-dienoyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | Authors: | Torkko, J.M, Koivuranta, K.T, Kastaniotis, A.J, Airenne, T.T, Glumoff, T, Ilves, M, Hartig, A, Gurvitz, A, Hiltunen, J.K. | Deposit date: | 2002-11-25 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers. J.Biol.Chem., 278, 2003
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3P6G
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![BU of 3p6g by Molmil](/molmil-images/mine/3p6g) | |
3MKV
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![BU of 3mkv by Molmil](/molmil-images/mine/3mkv) | Crystal structure of amidohydrolase eaj56179 | Descriptor: | CARBONATE ION, GLYCEROL, PUTATIVE AMIDOHYDROLASE, ... | Authors: | Patskovsky, Y, Bonanno, J, Ozyurt, S, Sauder, J.M, Freeman, J, Wu, B, Smith, D, Bain, K, Rodgers, L, Wasserman, S.R, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2010-04-15 | Release date: | 2010-04-28 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily . Biochemistry, 49, 2010
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1ND1
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![BU of 1nd1 by Molmil](/molmil-images/mine/1nd1) | Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities. | Descriptor: | BaP1, ZINC ION | Authors: | Watanabe, L, Shannon, J.D, Valente, R.H, Rucavado, A, Alape-Giron, A, Kamiguti, A.S, Theakston, R.D, Fox, J.W, Gutierrez, J.M, Arni, R.K. | Deposit date: | 2002-12-06 | Release date: | 2003-11-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities Protein Sci., 12, 2003
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1QPS
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![BU of 1qps by Molmil](/molmil-images/mine/1qps) | THE CRYSTAL STRUCTURE OF A POST-REACTIVE COGNATE DNA-ECO RI COMPLEX AT 2.50 A IN THE PRESENCE OF MN2+ ION | Descriptor: | 5'-D(*AP*AP*TP*TP*CP*GP*CP*GP*)-3', 5'-D(*TP*CP*GP*CP*GP*)-3', ENDONUCLEASE ECORI, ... | Authors: | Horvath, M, Choi, J, Kim, Y, Wilkosz, P, Rosenberg, J.M. | Deposit date: | 1999-05-28 | Release date: | 1999-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Integration of Recognition and Cleavage: X-Ray Structures of Pre- Transition State and Post-Reactive DNA-Eco RI Endonuclease Complexes To be Published
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3MPH
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![BU of 3mph by Molmil](/molmil-images/mine/3mph) | The structure of human diamine oxidase complexed with an inhibitor aminoguanidine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive amine oxidase, CALCIUM ION, ... | Authors: | McGrath, A.P, Guss, J.M. | Deposit date: | 2010-04-27 | Release date: | 2010-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Correlation of active site metal content in human diamine oxidase with trihydroxyphenylalanine quinone cofactor biogenesis Biochemistry, 49, 2010
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4CVW
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![BU of 4cvw by Molmil](/molmil-images/mine/4cvw) | Structure of the barley limit dextrinase-limit dextrinase inhibitor complex | Descriptor: | CALCIUM ION, LIMIT DEXTRINASE, LIMIT DEXTRINASE INHIBITOR | Authors: | Moeller, M.S, Vester-Christensen, M.B, Jensen, J.M, Abou Hachem, M, Henriksen, A, Svensson, B. | Deposit date: | 2014-03-31 | Release date: | 2015-04-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Crystal Structure of Barley Limit Dextrinase:Limit Dextrinase Inhibitor (Ld:Ldi) Complex Reveals Insights Into Mechanism and Diversity of Cereal-Type Inhibitors. J.Biol.Chem., 290, 2015
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