1RSI

DHNA complex with 2-Amino-5-bromo-3-hydroxy-6-phenylpyrimidine

Summary for 1RSI
Related1RR5 1RRI 1RRW 1RRY 1RS2 1RS4 1RSD
DescriptorDihydroneopterin aldolase, 2-AMINO-5-BROMO-6-PHENYLPYRIMIDIN-4-OL (2 entities in total)
Functional Keywordsdhna, 7, 8-dihydroneopterin aldolase, 2-amino-5-bromo-3-hydroxy-6-phenylpyrimidine, lyase
Biological sourceStaphylococcus aureus
Total number of polymer chains1
Total formula weight14035.73
Authors
Primary citationBetz, S.F.,Beutel, B.A.,Condroski, K.R.,Harlan, J.E.,Jakob, C.G.,Lerner, C.G.,Magdalinos, P.,McCall, J.O.,Meadows, R.P.,Merrick, S.M.,Nienaber, V.L.,Sanders, W.J.,Severin, J.M.,Stamper, G.F.,Stoll, V.S.,Swanson, S.J.,Wagner, R.,Walter, K.A.
Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization.
J.Med.Chem., 47:1709-1718, 2004
PubMed: 15027862
DOI: 110.1021/jm030497y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB Foundation
wwPDBRCSB PDBPDBeBMRBAdv. SearchSearch help

178938

PDB entries from 2021-06-16