5E0W
| Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(4-hydroxyphenyl)cyclohexylidene]methanediyl}diphenol | Descriptor: | 4,4'-{[(3S)-3-(4-hydroxyphenyl)cyclohexylidene]methanediyl}diphenol, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | Deposit date: | 2015-09-29 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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6DLA
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4WUT
| CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM AGROBACTERIUM VITIS (Avi_5133, TARGET EFI-511220) WITH BOUND D-FUCOSE | Descriptor: | ABC transporter substrate binding protein (Ribose), CALCIUM ION, CHLORIDE ION, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-11-03 | Release date: | 2014-12-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM AGROBACTERIUM VITIS (Avi_5133, TARGET EFI-511220) WITH BOUND D-FUCOSE To be published
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4X09
| Structure of human RNase 6 in complex with sulphate anions | Descriptor: | GLYCEROL, Ribonuclease K6, SULFATE ION | Authors: | Prats-Ejarque, G, Arranz-Trullen, J, Blanco, J.A, Pulido, D, Moussaoui, M, Boix, E. | Deposit date: | 2014-11-21 | Release date: | 2016-04-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.722 Å) | Cite: | The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement. Biochem.J., 473, 2016
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5EBH
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5EC6
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249D
| STRUCTURAL COMPARISON BETWEEN THE D(CTAG) SEQUENCE IN OLIGONUCLEOTIDES AND TRP AND MET REPRESSOR-OPERATOR COMPLEXES | Descriptor: | CALCIUM ION, DNA (5'-D(*CP*GP*CP*TP*CP*TP*AP*GP*AP*GP*CP*G)-3') | Authors: | Urpi, L, Tereshko, V, Malinina, L, Huynh-Dinh, T, Subirana, J.A. | Deposit date: | 1996-02-22 | Release date: | 1996-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural comparison between the d(CTAG) sequence in oligonucleotides and trp and met repressor-operator complexes. Nat.Struct.Biol., 3, 1996
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3BJ4
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2A7Q
| Crystal structure of human dCK complexed with clofarabine and ADP | Descriptor: | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ... | Authors: | Zhang, Y, Secrist III, J.A, Ealick, S.E. | Deposit date: | 2005-07-05 | Release date: | 2006-01-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr.,Sect.D, 62, 2006
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1YHI
| Uncyclized precursor structure of S65A Y66S R96A GFP variant | Descriptor: | Green Fluorescent Protein | Authors: | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2005-01-08 | Release date: | 2005-02-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Understanding GFP Chromophore Biosynthesis: Controlling Backbone Cyclization and Modifying Post-translational Chemistry(,). Biochemistry, 44, 2005
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4WN9
| Structure of the Nitrogenase MoFe Protein from Clostridium pasteurianum Pressurized with Xenon | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Morrison, C.N, Hoy, J.A, Rees, D.C. | Deposit date: | 2014-10-11 | Release date: | 2015-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Substrate Pathways in the Nitrogenase MoFe Protein by Experimental Identification of Small Molecule Binding Sites. Biochemistry, 54, 2015
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4WT7
| Crystal structure of an ABC transporter solute binding protein (IPR025997) from Agrobacterium vitis (Avi_5165, Target EFI-511223) with bound allitol | Descriptor: | ABC transporter substrate binding protein (Ribose), CHLORIDE ION, D-allitol | Authors: | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-10-29 | Release date: | 2014-11-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of an ABC transporter solute binding protein (IPR025997) from Agrobacterium vitis (Avi_5165, Target EFI-511223) with bound allitol To be published
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1YJ2
| Cyclized, non-dehydrated post-translational product for S65A Y66S H148G GFP variant | Descriptor: | 1,2-ETHANEDIOL, Green Fluorescent Protein, MAGNESIUM ION | Authors: | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2005-01-13 | Release date: | 2005-02-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Understanding GFP Chromophore Biosynthesis: Controlling Backbone Cyclization and Modifying Post-translational Chemistry. Biochemistry, 44, 2005
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4WWQ
| Apo structure of the Grb7 SH2 domain | Descriptor: | Growth factor receptor-bound protein 7, MALONIC ACID | Authors: | Watson, G.M, Ambaye, N.D, Wilce, M.C, Wilce, J.A. | Deposit date: | 2014-11-12 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target. J.Med.Chem., 58, 2015
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6DAO
| NahE WT selenomethionine | Descriptor: | Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | Authors: | Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P. | Deposit date: | 2018-05-01 | Release date: | 2019-05-08 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.939 Å) | Cite: | Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily. Biochemistry, 57, 2018
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1YJF
| Cyclized post-translational product for S65A Y66S (GFPhal) green fluorescent protein variant | Descriptor: | Green Fluorescent Protein, MAGNESIUM ION | Authors: | Barondeau, D.P, Kassmann, C.J, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2005-01-14 | Release date: | 2005-02-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Understanding GFP Chromophore Biosynthesis: Controlling Backbone Cyclization and Modifying Post-translational Chemistry. Biochemistry, 44, 2005
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4X6S
| Grb7 SH2 domain with phosphotyrosine mimetic inhibitor peptide | Descriptor: | Growth factor receptor-bound protein 7, Phosphotyrosine mimetic inhibitor peptide G7-TEM1 | Authors: | Watson, G.M, Panjikar, S, Wilce, M.C, Wilce, J.A. | Deposit date: | 2014-12-09 | Release date: | 2015-09-23 | Last modified: | 2015-10-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target. J.Med.Chem., 58, 2015
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5EHD
| Crystal structure of human nucleophosmin-core in complex with cytochrome c | Descriptor: | CHLORIDE ION, Nucleophosmin | Authors: | Bernardo-Garcia, N, Hermoso, J.A, Gonzalez-Arzola, K, Diaz-Moreno, I, De la Rosa, M.A. | Deposit date: | 2015-10-28 | Release date: | 2016-11-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of human nucleophosmin-core in complex with cytochrome c To Be Published
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6DS9
| Elongated version of a de novo designed three helix bundle structure (GRa3D) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, THIOCYANATE ION, ... | Authors: | Koebke, K.J, Ruckthong, L.R, Meagher, J.L, Stuckey, J.A, Pecoraro, V.L. | Deposit date: | 2018-06-13 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Clarifying the Copper Coordination Environment in a de Novo Designed Red Copper Protein. Inorg Chem, 57, 2018
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4WNA
| Structure of the Nitrogenase MoFe Protein from Azotobacter vinelandii Pressurized with Xenon | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Morrison, C.N, Hoy, J.A, Zhang, L, Einsle, O, Rees, D.C. | Deposit date: | 2014-10-11 | Release date: | 2015-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substrate Pathways in the Nitrogenase MoFe Protein by Experimental Identification of Small Molecule Binding Sites. Biochemistry, 54, 2015
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3C1P
| Crystal Structure of an alternating D-Alanyl, L-Homoalanyl PNA | Descriptor: | Peptide Nucleic Acid DLY-HGL-AGD-LHC-AGD-LHC-CUD-LYS | Authors: | Cuesta-Seijo, J.A, Sheldrick, G.M, Zhang, J, Diederichsen, U. | Deposit date: | 2008-01-23 | Release date: | 2009-01-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Continuous beta-turn fold of an alternating alanyl/homoalanyl peptide nucleic acid. Acta Crystallogr.,Sect.D, 68, 2012
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4WS9
| Crystal structure of sMAT N159G from Sulfolobus solfataricus | Descriptor: | PHOSPHATE ION, S-adenosylmethionine synthase | Authors: | Wang, F, Brady, E.L, Singh, S, Clinger, J.A, Huber, T.D, Thorson, J.S, Phillips Jr, G.N. | Deposit date: | 2014-10-26 | Release date: | 2014-11-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Crystal structure of sMAT N159G from Sulfolobus solfataricus. To Be Published
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4WZZ
| CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM CLOSTRIDIUM PHYTOFERMENTAS (Cphy_0583, TARGET EFI-511148) WITH BOUND L-RHAMNOSE | Descriptor: | 1,2-ETHANEDIOL, Putative sugar ABC transporter, substrate-binding protein, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2014-11-20 | Release date: | 2014-12-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CRYSTAL STRUCTURE OF AN ABC TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM CLOSTRIDIUM PHYTOFERMENTAS (Cphy_0583, TARGET EFI-511148) WITH BOUND L-RHAMNOSE To be published
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6DXI
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5EVG
| Crystal structure of a Francisella virulence factor FvfA in the orthorhombic form | Descriptor: | Francisella virulence factor | Authors: | Kolappan, S, Lo, K.Y, Shen, C.L.J, Guttman, J.A, Craig, L. | Deposit date: | 2015-11-19 | Release date: | 2016-10-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure of the conserved Francisella virulence protein FvfA. Acta Crystallogr D Struct Biol, 73, 2017
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