7AK8
| Structure of Salmonella TacT1 toxin bound to TacA1 antitoxin C-terminal peptide | Descriptor: | ACETYL COENZYME *A, GCN5 family acetyltransferase, GLYCEROL, ... | Authors: | Grabe, G.J, Morgan, R.M.L, Helaine, S, Hare, S.A. | Deposit date: | 2020-09-30 | Release date: | 2021-08-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nat.Chem.Biol., 17, 2021
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7AK7
| Structure of Salmonella TacT2 toxin bound to TacA2 antitoxin | Descriptor: | ACETYL COENZYME *A, Acetyltransferase, CHLORIDE ION, ... | Authors: | Grabe, G.J, Morgan, R.M.L, Hare, S.A, Helaine, S. | Deposit date: | 2020-09-30 | Release date: | 2021-08-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nat.Chem.Biol., 17, 2021
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7AK9
| Structure of Salmonella TacT3 toxin bound to TacA3 antitoxin C-terminal peptide | Descriptor: | ABC transporter, Acetyltransferase, DEPHOSPHO COENZYME A | Authors: | Grabe, G.J, Morgan, R.M.L, Hare, S.A, Helaine, S. | Deposit date: | 2020-09-30 | Release date: | 2021-08-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nat.Chem.Biol., 17, 2021
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5LQ6
| Salmonella effector SpvD - R161 variant | Descriptor: | SODIUM ION, Virulence protein vsdE | Authors: | Zhang, Y, Grabe, G.J, Rolhion, N, Yang, Y, Holden, D.W, Hare, S.A. | Deposit date: | 2016-08-16 | Release date: | 2016-11-02 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence. J. Biol. Chem., 291, 2016
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5LQ7
| Salmonella effector SpvD - G161 variant | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Przydacz, M, Grabe, G.J, Holden, D.W, Hare, S.A. | Deposit date: | 2016-08-16 | Release date: | 2016-11-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence. J. Biol. Chem., 291, 2016
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5N3W
| Crystal structure of LTA4H bound to a selective inhibitor against LTB4 generation | Descriptor: | 3-[2-(2-hydroxyphenyl)ethyl]-5-methoxy-phenol, ACETATE ION, IMIDAZOLE, ... | Authors: | Wong, C.T, Low, C.M, Snelgrove, R.J, Hare, S.A. | Deposit date: | 2017-02-09 | Release date: | 2017-03-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The development of novel LTA4H modulators to selectively target LTB4 generation. Sci Rep, 7, 2017
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5EC6
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5EE2
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5EE4
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5FVJ
| Crystal structure of TacT (tRNA acetylating toxin) from Salmonella | Descriptor: | ACETYL COENZYME *A, PUTATIVE ACETYLTRANSFERASE | Authors: | Przydacz, M, Wong, C.T, Cheverton, A.M, Gollan, B, Mylona, A, Helaine, S, Hare, S.A. | Deposit date: | 2016-02-08 | Release date: | 2016-06-01 | Last modified: | 2016-07-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A Salmonella Toxin Promotes Persister Formation Through Acetylation of tRNA. Mol.Cell, 63, 2016
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6G96
| Crystal structure of TacT3 (tRNA acetylating toxin) from Salmonella | Descriptor: | ACETYL COENZYME *A, Acetyltransferase, BICINE, ... | Authors: | Grabe, G.J, Rycroft, J.A, Gollan, B, Hall, A, Cheverton, A.M, Larrouy-Maumus, G, Hare, S.A, Helaine, S. | Deposit date: | 2018-04-10 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4766078 Å) | Cite: | Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection. Nat Commun, 9, 2018
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