3BJ4

The KCNQ1 (Kv7.1) C-terminus, a multi-tiered scaffold for subunit assembly and protein interaction

Summary for 3BJ4

Entry DOI	10.2210/pdb3bj4/pdb
Descriptor	Potassium voltage-gated channel subfamily KQT member 1, NICKEL (II) ION (3 entities in total)
Functional Keywords	coiled coil, alternative splicing, deafness, disease mutation, glycoprotein, ion transport, ionic channel, long qt syndrome, membrane, phosphoprotein, polymorphism, potassium, potassium channel, potassium transport, short qt syndrome, transmembrane, transport, voltage-gated channel, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Multi-pass membrane protein: P51787
Total number of polymer chains	2
Total formula weight	10907.05
Authors	Wiener, R.,Hirsch, J.A. (deposition date: 2007-12-03, release date: 2008-01-15, Last modification date: 2024-03-13)
Primary citation	Wiener, R.,Haitin, Y.,Shamgar, L.,Fernandez-Alonso, M.C.,Martos, A.,Chomsky-Hecht, O.,Rivas, G.,Attali, B.,Hirsch, J.A. The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction. J.Biol.Chem., 283:5815-5830, 2008 Cited by PubMed: 18165683 DOI: 10.1074/jbc.M707541200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation