3MP5
 
 | | Crystal Structure of Human Lyase R41M in complex with HMG-CoA | | 分子名称: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, Hydroxymethylglutaryl-CoA lyase, MAGNESIUM ION | | 著者 | Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. | | 登録日 | 2010-04-24 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
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2G1Z
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3M01
 | | The Crystal Structure of 5-epi-aristolochene synthase complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate | | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, ACETATE ION, Aristolochene synthase, ... | | 著者 | Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E. | | 登録日 | 2010-03-02 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
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3IFV
 | | Crystal structure of the Haloferax volcanii proliferating cell nuclear antigen | | 分子名称: | PCNA, SODIUM ION | | 著者 | Winter, J.A, Christofi, P, Morroll, S, Bunting, K.A. | | 登録日 | 2009-07-26 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation
Bmc Struct.Biol., 9, 2009
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4CYP
 | | Leishmania major N-myristoyltransferase in complex with a pyrrolidine inhibitor. | | 分子名称: | (3R)-4-(4-chlorophenyl)-1-[(3S,4R)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-1-yl]-3-hydroxybutan-1-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... | | 著者 | Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. | | 登録日 | 2014-04-14 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors.
J.Med.Chem., 57, 2014
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3IJQ
 | | Structure of dipeptide epimerase from Bacteroides thetaiotaomicron complexed with L-Ala-D-Glu; productive substrate binding. | | 分子名称: | ALANINE, D-GLUTAMIC ACID, MAGNESIUM ION, ... | | 著者 | Fedorov, A.A, Fedorov, E.V, Lukk, T, Gerlt, J.A, Almo, S.C. | | 登録日 | 2009-08-04 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3M5Z
 | | Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum | | 分子名称: | Orotidine 5'-phosphate decarboxylase, SULFATE ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-03-14 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation.
Biochemistry, 49, 2010
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2TIR
 | | CRYSTAL STRUCTURE ANALYSIS OF A MUTANT ESCHERICHIA COLI THIOREDOXIN IN WHICH LYSINE 36 IS REPLACED BY GLUTAMIC ACID | | 分子名称: | COPPER (II) ION, THIOREDOXIN | | 著者 | Nikkola, M, Gleason, F.K, Fuchs, J.A, Eklund, H. | | 登録日 | 1993-01-10 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure analysis of a mutant Escherichia coli thioredoxin in which lysine 36 is replaced by glutamic acid.
Biochemistry, 32, 1993
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6R9J
 | | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with A7 RNA | | 分子名称: | A7 RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | | 著者 | Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A. | | 登録日 | 2019-04-03 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.326 Å) | | 主引用文献 | The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
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6R9P
 | | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAUUAA RNA | | 分子名称: | AAUUAA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | | 著者 | Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A. | | 登録日 | 2019-04-03 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
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2GCA
 | | apo form of L. casei FPGS | | 分子名称: | Folylpolyglutamate synthase | | 著者 | Smith, C.A, Cross, J.A, Bognar, A.L, Sun, X. | | 登録日 | 2006-03-13 | | 公開日 | 2006-06-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mutation of Gly51 to serine in the P-loop of Lactobacillus casei folylpolyglutamate synthetase abolishes activity by altering the conformation of two adjacent loops.
Acta Crystallogr.,Sect.D, 62, 2006
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3H1P
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3H5G
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1BTQ
 | | THE SOLUTION STRUCTURES OF THE FIRST AND SECOND TRANSMEMBRANE-SPANNING SEGMENTS OF BAND 3 | | 分子名称: | BAND 3 ANION TRANSPORT PROTEIN | | 著者 | Gargaro, A.R, Bloomberg, G.B, Dempsey, C.E, Murray, M, Tanner, M.J.A. | | 登録日 | 1994-08-03 | | 公開日 | 1994-11-30 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structures of the first and second transmembrane-spanning segments of band 3.
Eur.J.Biochem., 221, 1994
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3H8I
 | | The first X-ray structure of a sulfide:quinone oxidoreductase: Insights into sulfide oxidation mechanism | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADH oxidase, PHOSPHATE ION, ... | | 著者 | Brito, J.A, Sousa, F.L, Stelter, M, Bandeiras, T.M, Vonrhein, C, Teixeira, M, Pereira, M.M, Archer, M. | | 登録日 | 2009-04-29 | | 公開日 | 2009-06-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural and functional insights into sulfide:quinone oxidoreductase.
Biochemistry, 48, 2009
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6R9O
 | | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with AAGGA RNA | | 分子名称: | AAGGA RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | | 著者 | Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A. | | 登録日 | 2019-04-03 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.319 Å) | | 主引用文献 | The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases.
Nat.Struct.Mol.Biol., 26, 2019
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2GNV
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2ONC
 | | Crystal structure of human DPP-4 | | 分子名称: | 2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Feng, J, Zhang, Z, Wallace, M.B, Stafford, J.A, Kaldor, S.W, Kassel, D.B, Navre, M, Shi, L, Skene, R.J, Asakawa, T, Takeuchi, K, Xu, R, Webb, D.R, Gwaltney, S.L. | | 登録日 | 2007-01-23 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV.
J.Med.Chem., 50, 2007
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2GVL
 | | Crystal Structure of Murine NMPRTase | | 分子名称: | Nicotinamide phosphoribosyltransferase | | 著者 | Khan, J.A, Tao, X, Tong, L. | | 登録日 | 2006-05-02 | | 公開日 | 2006-07-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
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1BRV
 | | SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES | | 分子名称: | PROTEIN G | | 著者 | Doreleijers, J.F, Langedijk, J.P.M, Hard, K, Rullmann, J.A.C, Boelens, R, Schaaper, W.M, Van Oirschot, J.T, Kaptein, R. | | 登録日 | 1996-03-29 | | 公開日 | 1997-06-05 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the immunodominant region of protein G of bovine respiratory syncytial virus.
Biochemistry, 35, 1996
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6EJ1
 | | Crystal structure of KDM5B in complex with KDOPZ48a. | | 分子名称: | 1,2-ETHANEDIOL, 5-[1-[1-(2-chloranylethanoyl)piperidin-4-yl]pyrazol-4-yl]-7-oxidanylidene-6-propan-2-yl-4~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile, DIMETHYL SULFOXIDE, ... | | 著者 | Srikannathasan, V, Newman, J.A, Szykowska, A, Wright, M, Ruda, G.F, Vazquez-Rodriguez, S.A, Kupinska, K, Strain-Damerell, C, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A, Bountra, C, Oppermann, U, Huber, K, von Delft, F. | | 登録日 | 2017-09-19 | | 公開日 | 2018-05-02 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal structure of KDM5B in complex with KDOPZ48a.
to be published
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2H4R
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3M41
 | | Crystal structure of the mutant V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum | | 分子名称: | GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-03-10 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Conformational changes in orotidine 5'-monophosphate decarboxylase: "remote" residues that stabilize the active conformation.
Biochemistry, 49, 2010
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3M52
 | | Crystal structure of the BTB domain from the Miz-1/ZBTB17 transcription regulator | | 分子名称: | ACETATE ION, ZINC ION, Zinc finger and BTB domain-containing protein 17 | | 著者 | Stogios, P.J, Cuesta-Seijo, J.A, Chen, L, Prive, G.G. | | 登録日 | 2010-03-12 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Insights into Strand Exchange in BTB Domain Dimers from the Crystal Structures of FAZF and Miz1.
J.Mol.Biol., 400, 2010
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5HAN
 | | Structure function studies of R. palustris RubisCO (S59F mutant; CABP-bound) | | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, Ribulose bisphosphate carboxylase | | 著者 | Arbing, M.A, Leong, J.G, Varaljay, V.A, Satagopan, S, North, J.A, Tabita, F.R. | | 登録日 | 2015-12-30 | | 公開日 | 2017-01-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure function studies of R. palustris RubisCO
To Be Published
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