3MP5
Crystal Structure of Human Lyase R41M in complex with HMG-CoA
Summary for 3MP5
Entry DOI | 10.2210/pdb3mp5/pdb |
Related | 3MP3 3MP4 |
Descriptor | Hydroxymethylglutaryl-CoA lyase, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | ketogenic enzyme, human hmg-coa lyase, 3-hydroxyl-3-methylglutaryl-coa, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P35914 |
Total number of polymer chains | 6 |
Total formula weight | 190265.02 |
Authors | Fu, Z.,Runquist, J.A.,Montgomery, C.,Miziorko, H.M.,Kim, J.-J.P. (deposition date: 2010-04-24, release date: 2010-06-16, Last modification date: 2023-09-06) |
Primary citation | Fu, Z.,Runquist, J.A.,Montgomery, C.,Miziorko, H.M.,Kim, J.J. Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. J.Biol.Chem., 285:26341-26349, 2010 Cited by PubMed: 20558737DOI: 10.1074/jbc.M110.139931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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