2GVL

Crystal Structure of Murine NMPRTase

Summary for 2GVL

Entry DOI	10.2210/pdb2gvl/pdb
Descriptor	Nicotinamide phosphoribosyltransferase (2 entities in total)
Functional Keywords	visfatin, pbef, nmprtase, cancer, fk866, transferase
Biological source	Mus musculus (house mouse)
Cellular location	Cytoplasm: Q99KQ4
Total number of polymer chains	2
Total formula weight	111137.13
Authors	Khan, J.A.,Tao, X.,Tong, L. (deposition date: 2006-05-02, release date: 2006-07-25, Last modification date: 2011-07-13)
Primary citation	Khan, J.A.,Tao, X.,Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13:582-588, 2006 Cited by PubMed: 16783377 DOI: 10.1038/nsmb1105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation