7S4R
| Serial Macromolecular Crystallography at ALBA Synchrotron Light Source - alpha Spectrin-SH3 domain | 分子名称: | Spectrin alpha chain, non-erythrocytic 1 | 著者 | Martin-Garcia, J.M, Botha, S, Hu, H, Jernigan, R, Castellvi, A, Lisova, S, Gil, F, Calisto, B, Crespo, I, Roy-Chowdbury, S, Grieco, A, Ketawala, G, Weierstall, U, Spence, J, Fromme, P, Zatsepin, N, Boer, R, Carpena, X. | 登録日 | 2021-09-09 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Serial macromolecular crystallography at ALBA Synchrotron Light Source. J.Synchrotron Radiat., 29, 2022
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8D2O
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 2) | 分子名称: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | 著者 | Rai, J, Das, A, Li, H. | 登録日 | 2022-05-30 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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8D2L
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 1) | 分子名称: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ... | 著者 | Rai, J, Das, A, Li, H. | 登録日 | 2022-05-30 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.21 Å) | 主引用文献 | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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5WMN
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2Q19
| 2-keto-3-deoxy-D-arabinonate dehydratase apo form | 分子名称: | 2-keto-3-deoxy-D-arabinonate dehydratase | 著者 | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | 登録日 | 2007-05-24 | 公開日 | 2008-04-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily. J.Mol.Biol., 379, 2008
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8D2Q
| Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 1) | 分子名称: | CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ... | 著者 | Rai, J, Das, A, Li, H. | 登録日 | 2022-05-30 | 公開日 | 2023-12-20 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Coupled catalytic states and the role of metal coordination in Cas9. Nat Catal, 6, 2023
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5K6P
| The NMR structure of the m domain tri-helix bundle and C2 of human cardiac Myosin Binding Protein C | 分子名称: | Myosin-binding protein C, cardiac-type | 著者 | Michie, K.A, Kwan, A.H, Tung, C.S, Guss, J.M, Trewhella, J. | 登録日 | 2016-05-25 | 公開日 | 2016-11-09 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A Highly Conserved Yet Flexible Linker Is Part of a Polymorphic Protein-Binding Domain in Myosin-Binding Protein C. Structure, 24, 2016
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8CR6
| mouse Interleukin-12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit alpha, Interleukin-12 subunit beta, ... | 著者 | Merceron, R, Felix, J, Lambert, E, Bloch, Y, Savvides, S.N. | 登録日 | 2023-03-07 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8SH0
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8CR5
| Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 subunit beta, ... | 著者 | Merceron, R, Bloch, Y, Felix, J, Savvides, S.N. | 登録日 | 2023-03-07 | 公開日 | 2024-02-07 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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5JPW
| Molecular basis for protein recognition specificity of the DYNLT1/Tctex1 canonical binding groove. Characterization of the interaction with activin receptor IIB | 分子名称: | Dynein light chain Tctex-type 1,Cytoplasmic dynein 1 intermediate chain 2 | 著者 | Rodriguez-Crespo, I, Merino-Gracia, J, Bruix, M, Zamora-Carreras, H. | 登録日 | 2016-05-04 | 公開日 | 2016-08-17 | 最終更新日 | 2024-07-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Basis for the Protein Recognition Specificity of the Dynein Light Chain DYNLT1/Tctex1: CHARACTERIZATION OF THE INTERACTION WITH ACTIVIN RECEPTOR IIB. J.Biol.Chem., 291, 2016
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1LPV
| DROSOPHILA MELANOGASTER DOUBLESEX (DSX), NMR, 18 STRUCTURES | 分子名称: | Doublesex protein, ZINC ION | 著者 | Zhu, L, Wilken, J, Phillips, N, Narendra, U, Chan, G, Stratton, S, Kent, S, Weiss, M.A. | 登録日 | 2002-05-08 | 公開日 | 2002-10-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers. Genes Dev., 14, 2000
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8SH1
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1X7Y
| Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase | 分子名称: | 2-oxoisovalerate dehydrogenase alpha subunit, 2-oxoisovalerate dehydrogenase beta subunit, CHLORIDE ION, ... | 著者 | Wynn, R.M, Kato, M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T. | 登録日 | 2004-08-16 | 公開日 | 2004-11-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation Structure, 12, 2004
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8CQT
| Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_1316) | 分子名称: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, Putative NADH dehydrogenase/NAD(P)H nitroreductase | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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5KR4
| Directed Evolution of Transaminases By Ancestral Reconstruction. Using Old Proteins for New Chemistries | 分子名称: | 1,2-ETHANEDIOL, 4-aminobutyrate transaminase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Wilding, M, Newman, J, Peat, T.S, Scott, C. | 登録日 | 2016-07-06 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Reverse engineering: transaminase biocatalyst development using ancestral sequence reconstruction Green Chemistry, 19, 2017
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8CQU
| Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_1680) | 分子名称: | CITRIC ACID, Putative NADH dehydrogenase/NAD(P)H nitroreductase, TERTIARY-BUTYL ALCOHOL | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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8CQV
| Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_3392) | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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8CQS
| Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_0217) | 分子名称: | FLAVIN MONONUCLEOTIDE, Nitroreductase-like protein, PHOSPHATE ION | 著者 | Blaha, J, Gratzl, S, Mortensen, S.A, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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5KK8
| Crystal structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase | 著者 | Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2016-06-21 | 公開日 | 2017-06-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs. Mol.Biochem.Parasitol., 2019
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7S0F
| Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein | 分子名称: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. | 登録日 | 2021-08-30 | 公開日 | 2021-11-17 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28, 2021
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1X6W
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8CAS
| Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8CBJ
| Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex | 分子名称: | 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-25 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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5KRL
| Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the A-CD ring estrogen, (1S,7aS)-5-(2-chloro-4-hydroxyphenyl)-7a-methyl-2,3,3a,4,7,7a-hexahydro-1H-inden-1-ol | 分子名称: | (1~{S},3~{a}~{R},7~{a}~{S})-5-(2-chloranyl-4-oxidanyl-phenyl)-2,3,3~{a},4,7,7~{a}-hexahydro-1~{H}-inden-1-ol, Estrogen receptor, NCOA2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Nowak, J, Kojetin, D.J, Elemento, O, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2016-07-07 | 公開日 | 2017-01-18 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chem Biol, 24, 2017
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