8CR6
mouse Interleukin-12
Summary for 8CR6
Entry DOI | 10.2210/pdb8cr6/pdb |
Related | 8C7M 8CR5 |
Descriptor | Interleukin-12 subunit beta, Interleukin-12 subunit alpha, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | cytokine, inflammation, immunity, heterodimer |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 67493.65 |
Authors | Merceron, R.,Felix, J.,Lambert, E.,Bloch, Y.,Savvides, S.N. (deposition date: 2023-03-07, release date: 2024-02-07, Last modification date: 2024-05-01) |
Primary citation | Bloch, Y.,Felix, J.,Merceron, R.,Provost, M.,Symakani, R.A.,De Backer, R.,Lambert, E.,Mehdipour, A.R.,Savvides, S.N. Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31:591-597, 2024 Cited by PubMed: 38287195DOI: 10.1038/s41594-023-01190-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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