8CR6
mouse Interleukin-12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-12 subunit beta | polymer | 335 | 38282.4 | 1 | UniProt (P43432) Pfam (PF10420) | Mus musculus (house mouse) | IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40 |
| 2 | B (B) | Interleukin-12 subunit alpha | polymer | 253 | 28403.5 | 1 | UniProt (P43431) Pfam (PF03039) | Mus musculus (house mouse) | IL-12A,Cytotoxic lymphocyte maturation factor 35 kDa subunit,CLMF p35,IL-12 subunit p35 |
| 3 | C (C) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
B: 1 - 215 (UniProt: P43431)
| PDB | External Database | Details |
|---|---|---|
| Gly 216 | - | expression tag |
| Thr 217 | - | expression tag |
| Ser 218 | - | expression tag |
| Asp 219 | - | expression tag |
| Glu 220 | - | expression tag |
| Val 221 | - | expression tag |
| Asp 222 | - | expression tag |
| Gly 223 | - | expression tag |
| Gly 224 | - | expression tag |
| Ser 225 | - | expression tag |
| Gly 226 | - | expression tag |
| Gly 227 | - | expression tag |
| Ser 228 | - | expression tag |
| Gly 229 | - | expression tag |
| Leu 230 | - | expression tag |
| Asn 231 | - | expression tag |
| Asp 232 | - | expression tag |
| Ile 233 | - | expression tag |
| Phe 234 | - | expression tag |
| Glu 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Gln 237 | - | expression tag |
| Lys 238 | - | expression tag |
| Ile 239 | - | expression tag |
| Glu 240 | - | expression tag |
| Trp 241 | - | expression tag |
| His 242 | - | expression tag |
| Glu 243 | - | expression tag |
| Gly 244 | - | expression tag |
| Arg 245 | - | expression tag |
| Thr 246 | - | expression tag |
| Lys 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66685.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 67493.7 |
