8CR5
Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta.
Summary for 8CR5
| Entry DOI | 10.2210/pdb8cr5/pdb |
| Descriptor | Interleukin-12 subunit beta, Interleukin-12 receptor subunit beta-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | complex, inflammation, glycoprotein, immunity, cytokine |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 69963.80 |
| Authors | Merceron, R.,Bloch, Y.,Felix, J.,Savvides, S.N. (deposition date: 2023-03-07, release date: 2024-02-07) |
| Primary citation | Bloch, Y.,Felix, J.,Merceron, R.,Provost, M.,Symakani, R.A.,De Backer, R.,Lambert, E.,Mehdipour, A.R.,Savvides, S.N. Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38287195DOI: 10.1038/s41594-023-01190-6 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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