8CR5
Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Interleukin-12 subunit beta | polymer | 344 | 39382.5 | 1 | UniProt (P43432) Pfam (PF10420) In PDB | Mus musculus (house mouse) | IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40 |
| 2 | B | Interleukin-12 receptor subunit beta-1 | polymer | 265 | 29611.4 | 1 | UniProt (Q60837) In PDB | Mus musculus (house mouse) | IL-12 receptor subunit beta-1,IL-12R subunit beta-1,IL-12R-beta-1,IL-12 receptor beta component |
| 3 | C | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A: 1 - 335 (UniProt: P43432)
B: 20 - 258 (UniProt: Q60837)
| PDB | External Database | Details |
|---|---|---|
| Ser 197 | Cys 197 | engineered mutation |
| Gly 336 | - | expression tag |
| Thr 337 | - | expression tag |
| Lys 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
| His 341 | - | expression tag |
| His 342 | - | expression tag |
| His 343 | - | expression tag |
| His 344 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Gly 4 | - | expression tag |
| Val 5 | - | expression tag |
| Lys 6 | - | expression tag |
| Val 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Phe 9 | - | expression tag |
| Ala 10 | - | expression tag |
| Leu 11 | - | expression tag |
| Ile 12 | - | expression tag |
| Cys 13 | - | expression tag |
| Ile 14 | - | expression tag |
| Ala 15 | - | expression tag |
| Val 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Glu 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Gly 259 | - | expression tag |
| Thr 260 | - | expression tag |
| Lys 261 | - | expression tag |
| His 262 | - | expression tag |
| His 263 | - | expression tag |
| His 264 | - | expression tag |
| His 265 | - | expression tag |
| His 266 | - | expression tag |
| His 267 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68993.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 748.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 69963.8 |
