8YCM
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![BU of 8ycm by Molmil](/molmil-images/mine/8ycm) | Monomeric Human STK19 | 分子名称: | Isoform 4 of Inactive serine/threonine-protein kinase 19, SULFATE ION | 著者 | Li, J, Ma, X, Dong, Z. | 登録日 | 2024-02-18 | 公開日 | 2024-03-06 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19. Sci Rep, 14, 2024
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9B4H
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![BU of 9b4h by Molmil](/molmil-images/mine/9b4h) | Chlamydomonas reinhardtii mastigoneme filament | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain-containing protein, Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein, ... | 著者 | Dai, J, Ma, M, Zhang, R, Brown, A. | 登録日 | 2024-03-20 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices. Cell, 2024
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8YZN
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9B7F
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![BU of 9b7f by Molmil](/molmil-images/mine/9b7f) | S_SAD structure of HEWL using lossless default compression | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | 著者 | Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. | 登録日 | 2024-03-27 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published
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5LNF
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![BU of 5lnf by Molmil](/molmil-images/mine/5lnf) | Solution NMR structure of farnesylated PEX19, C-terminal domain | 分子名称: | FARNESYL, Peroxisomal biogenesis factor 19 | 著者 | Emmanouilidis, L, Schuetz, U, Tripsianes, K, Madl, T, Radke, J, Rucktaeschel, R, Wilmanns, M, Schliebs, W, Erdmann, R, Sattler, M. | 登録日 | 2016-08-04 | 公開日 | 2017-03-15 | 最終更新日 | 2019-09-11 | 実験手法 | SOLUTION NMR | 主引用文献 | Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19. Nat Commun, 8, 2017
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5M1L
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8YZO
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9B7E
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![BU of 9b7e by Molmil](/molmil-images/mine/9b7e) | S_SAD structure of HEWL using lossy compression data with a compression ratio of 422 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | 著者 | Jakoncic, J, Bernstein, H.J, Soares, A.S, Horvat, K. | 登録日 | 2024-03-27 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Investigation of fast and efficient lossless compression algorithms for macromolecular crystallography experiments To Be Published
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5LP6
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![BU of 5lp6 by Molmil](/molmil-images/mine/5lp6) | Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S. | 登録日 | 2016-08-11 | 公開日 | 2016-09-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Tools for the rational design of bivalent microtubule-targeting drugs. Biochem. Biophys. Res. Commun., 479, 2016
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5LPN
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![BU of 5lpn by Molmil](/molmil-images/mine/5lpn) | Structure of human Rab10 in complex with the bMERB domain of Mical-1 | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein-methionine sulfoxide oxidase MICAL1, ... | 著者 | Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M. | 登録日 | 2016-08-14 | 公開日 | 2016-08-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | bMERB domains are bivalent Rab8 family effectors evolved by gene duplication. Elife, 5, 2016
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5LU6
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![BU of 5lu6 by Molmil](/molmil-images/mine/5lu6) | Heptose isomerase mutant - H64Q | 分子名称: | 1,2-ETHANEDIOL, D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE, GLYCEROL, ... | 著者 | Vivoli, M, Harmer, N.J, Pang, J. | 登録日 | 2016-09-08 | 公開日 | 2017-12-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | A half-site multimeric enzyme achieves its cooperativity without conformational changes. Sci Rep, 7, 2017
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5LF3
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![BU of 5lf3 by Molmil](/molmil-images/mine/5lf3) | Human 20S proteasome complex with Bortezomib at 2.1 Angstrom | 分子名称: | CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... | 著者 | Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. | 登録日 | 2016-06-30 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
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5LGS
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![BU of 5lgs by Molmil](/molmil-images/mine/5lgs) | Crystal structure of mouse CARM1 in complex with ligand P2C3u | 分子名称: | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol, 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, ... | 著者 | Marechal, N, Troffer-Charlier, N, Cura, V, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-07-08 | 公開日 | 2017-03-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8XXN
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![BU of 8xxn by Molmil](/molmil-images/mine/8xxn) | Cryo-EM structure of the human 43S ribosome with PDCD4 | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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9AUC
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![BU of 9auc by Molmil](/molmil-images/mine/9auc) | Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calcitonin gene-related peptide 1, ... | 著者 | Cao, J, Belousoff, M.J, Wootten, D.L, Sexton, P.M. | 登録日 | 2024-02-28 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein. Biochemistry, 63, 2024
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5LWE
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![BU of 5lwe by Molmil](/molmil-images/mine/5lwe) | Crystal structure of the human CC chemokine receptor type 9 (CCR9) in complex with vercirnon | 分子名称: | C-C chemokine receptor type 9, CHOLESTEROL, MALONATE ION, ... | 著者 | Oswald, C, Rappas, M, Kean, J, Dore, A.S, Errey, J.C, Bennett, K, Deflorian, F, Christopher, J.A, Jazayeri, A, Mason, J.S, Congreve, M, Cooke, R.M, Marshall, F.H. | 登録日 | 2016-09-16 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Intracellular allosteric antagonism of the CCR9 receptor. Nature, 540, 2016
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6DA6
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![BU of 6da6 by Molmil](/molmil-images/mine/6da6) | Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes, apo form at 2.6 A resolution (P212121) | 分子名称: | GLYCEROL, MAGNESIUM ION, UNKNOWN LIGAND, ... | 著者 | Han, L, Rudolf, J.D, Chang, C.-Y, Miller, M.D, Soman, J, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2018-05-01 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway. ACS Chem. Biol., 13, 2018
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8Z1E
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![BU of 8z1e by Molmil](/molmil-images/mine/8z1e) | A homotrimeric GPCR architecture of the human cytomegalovirus (UL78) revealed by cryo-EM | 分子名称: | Uncharacterized protein UL78 | 著者 | Chen, Y, Li, Y, Zhou, Q, Cong, Z, Lin, S, Yan, J, Chen, X, Yang, D, Ying, T, Wang, M.-W. | 登録日 | 2024-04-11 | 公開日 | 2024-05-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | A homotrimeric GPCR architecture of the human cytomegalovirus revealed by cryo-EM. Cell Discov, 10, 2024
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8XXL
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![BU of 8xxl by Molmil](/molmil-images/mine/8xxl) | Cryo-EM structure of the human 40S ribosome with PDCD4 | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXM
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![BU of 8xxm by Molmil](/molmil-images/mine/8xxm) | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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5LZL
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![BU of 5lzl by Molmil](/molmil-images/mine/5lzl) | Pyrobaculum calidifontis 5-aminolaevulinic acid dehydratase | 分子名称: | Delta-aminolevulinic acid dehydratase, ZINC ION | 著者 | Azim, N, Erskine, P.T, Guo, J, Cooper, J.B. | 登録日 | 2016-09-30 | 公開日 | 2016-10-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | 主引用文献 | Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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5LZR
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![BU of 5lzr by Molmil](/molmil-images/mine/5lzr) | Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase in complex with tungstate and magnesium | 分子名称: | K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, TUNGSTATE(VI)ION | 著者 | Wilkinson, C, Kellosalo, J, Kajander, T, Goldman, A. | 登録日 | 2016-10-01 | 公開日 | 2016-12-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism. Nat Commun, 7, 2016
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5M32
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![BU of 5m32 by Molmil](/molmil-images/mine/5m32) | Human 26S proteasome in complex with Oprozomib | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Haselbach, D, Schrader, J, Lambrecht, F, Henneberg, F, Chari, A, Stark, H. | 登録日 | 2016-10-14 | 公開日 | 2017-07-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nat Commun, 8, 2017
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5LC8
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![BU of 5lc8 by Molmil](/molmil-images/mine/5lc8) | Crystal Structure of specific mutant from Pseudomonas aeruginosa Lipoxygenase at 1.8A resolution | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradec-5-enoyloxy)propyl (11Z)-octadec-11-enoate, Arachidonate 15-lipoxygenase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kalms, J, Banthiya, S, Galemou Yoga, E, Kuhn, H, Scheerer, P. | 登録日 | 2016-06-20 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity. Biochim. Biophys. Acta, 1862, 2017
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8YT5
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![BU of 8yt5 by Molmil](/molmil-images/mine/8yt5) | SP1746 treated with EDTA, in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, bis(5'-nucleosyl)-tetraphosphatase (symmetrical) | 著者 | Jin, Y, Niu, L, Ke, J. | 登録日 | 2024-03-25 | 公開日 | 2024-05-08 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 32, 2024
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