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PDB: 42289 件

2P7E
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Vanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State Stabilization
分子名称: 3' substrate strand, octameric fragment, 5' substrate strand, ...
著者Torelli, A.T, Krucinska, J, Wedekind, J.E.
登録日2007-03-20
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
1KCM
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Crystal Structure of Mouse PITP Alpha Void of Bound Phospholipid at 2.0 Angstroms Resolution
分子名称: Phosphatidylinositol Transfer Protein alpha
著者Schouten, A, Agianian, B, Westerman, J, Kroon, J, Wirtz, K.W.A, Gros, P.
登録日2001-11-09
公開日2002-05-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association.
EMBO J., 21, 2002
7WZE
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Structure of Transcriptional regulator from Bacillus subtilis (strain 168)
分子名称: Uncharacterized HTH-type transcriptional regulator YetL
著者Hong, M, Park, J.
登録日2022-02-17
公開日2022-04-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure-based molecular characterization of the YetL transcription factor from Bacillus subtilis.
Biochem.Biophys.Res.Commun., 607, 2022
2P7F
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The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme
分子名称: COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ...
著者Torelli, A.T, Krucinska, J, Wedekind, J.E.
登録日2007-03-20
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
4OPE
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Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS7
分子名称: NITRATE ION, NRPS/PKS
著者Osipiuk, J, Mack, J, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-02-05
公開日2014-02-19
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
2HOH
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RIBONUCLEASE T1 (N9A MUTANT) COMPLEXED WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PHOSPHATE ION, ...
著者Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J.
登録日1998-09-14
公開日1998-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
5WZJ
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Structure of APUM23-GGAUUUGACGG
分子名称: Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*UP*UP*UP*GP*AP*CP*GP*G)-3')
著者Bao, H, Wang, N, Wang, C, Jiang, Y, Wu, J, Shi, Y.
登録日2017-01-18
公開日2017-09-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
2PBN
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Crystal structure of the human tyrosine receptor phosphate gamma
分子名称: Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION
著者Bonanno, J.B, Freeman, J, Bain, K.T, Reyes, C, Pelletier, L, Jin, X, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-03-28
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
2HW5
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The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
分子名称: CROTONYL COENZYME A, Enoyl-CoA hydratase, MAGNESIUM ION
著者Turnbull, A.P, Salah, E, Niesen, F, Debreczeni, J, Ugochukwu, E, Pike, A.C.W, Kavanagh, K, Gileadi, O, Gorrec, F, Umeano, C, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2006-07-31
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
To be Published
2P62
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Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3
分子名称: Hypothetical protein PH0156
著者Fu, Z.-Q, Chen, L, Zhu, J, Swindell, J.T, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-16
公開日2007-04-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3
To be Published
2P6F
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Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors
分子名称: (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
著者Wu, J, Ding, J.
登録日2007-03-18
公開日2007-06-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
4O92
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Crystal structure of a Glutathione S-transferase from Pichia kudriavzevii (Issatchenkia orientalis), target EFI-501747
分子名称: Glutathione S-transferase, SULFATE ION
著者Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Glenn, A.S, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2013-12-31
公開日2014-01-15
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of a Glutathione S-transferase from Pichia kudriavzevii (Issatchenkia orientalis), target EFI-501747
TO BE PUBLISHED
2Y0C
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BceC mutation Y10S
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ...
著者Rocha, J, Popescu, A.O, Borges, P, Mil-Homens, D, Sa-Correia, I, Fialho, A.M, Frazao, C.
登録日2010-12-02
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of Burkholderia Cepacia Udp-Glucose Dehydrogenase (Ugd) Bcec and Role of Tyr10 in Final Hydrolysis of Ugd Thioester Intermediate.
J.Bacteriol., 193, 2011
2P7D
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BU of 2p7d by Molmil
A Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms Resolution
分子名称: 3' substrate strand, octameric fragment, 5' substrate strand, ...
著者Torelli, A.T, Krucinska, J, Wedekind, J.E.
登録日2007-03-20
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
5XRO
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BU of 5xro by Molmil
Galectin-10/Charcot-Leyden crystal protein variant Q74A crystal structure
分子名称: GLYCEROL, Galectin-10
著者Su, J.
登録日2017-06-08
公開日2018-01-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding.
Glycobiology, 28, 2018
5XGE
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Crystal structure of the PAS-GGDEF-EAL domain of PA0861 from Pseudomonas aeruginosa in complex with cyclic di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein PA0861
著者Liu, C, Liew, C.W, Sreekanth, R, Lescar, J.
登録日2017-04-13
公開日2017-12-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
5XKD
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Crystal structure of dibenzothiophene sulfone monooxygenase BdsA in complex with FMN at 2.4 angstrom
分子名称: Dibenzothiophene desulfurization enzyme A, FLAVIN MONONUCLEOTIDE
著者Gu, L, Su, T, Liu, S, Su, J.
登録日2017-05-07
公開日2018-05-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Structural and Biochemical Characterization of BdsA fromBacillus subtilisWU-S2B, a Key Enzyme in the "4S" Desulfurization Pathway.
Front Microbiol, 9, 2018
2VS2
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Neutron diffraction structure of endothiapepsin in complex with a gem- diol inhibitor.
分子名称: ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide
著者Coates, L, Tuan, H.-F, Tomanicek, S, Kovalevsky, A, Mustyakimov, M, Erskine, P, Cooper, J.
登録日2008-04-17
公開日2008-05-27
最終更新日2023-11-15
実験手法NEUTRON DIFFRACTION (2 Å)
主引用文献The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-Ray Diffraction
J.Am.Chem.Soc., 130, 2008
2ZGA
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HIV-1 protease in complex with a dimethylallyl decorated pyrrolidine based inhibitor (hexagonal space group)
分子名称: (3S,4S),-3,4-Bis-[(4-carbamoyl-benzensulfonyl)-(3-methyl-but-2-enyl)-amino]-pyrrolidine, Protease
著者Boettcher, J, Blum, A, Heine, A, Diederich, W.E, Klebe, G.
登録日2008-01-21
公開日2009-02-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Two Solutions for the Same Problem: Multiple Binding Modes of Pyrrolidine-Based HIV-1 Protease Inhibitors
J.Mol.Biol., 410, 2011
4MVN
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Crystal structure of the staphylococcal serine protease SplA in complex with a specific phosphonate inhibitor
分子名称: Serine protease splA, [(1S)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl]phosphonic acid
著者Zdzalik, M, Burchacka, E, Niemczyk, J.S, Pustelny, K, Popowicz, G.M, Wladyka, B, Dubin, A, Potempa, J, Sienczyk, M, Dubin, G, Oleksyszyn, J.
登録日2013-09-24
公開日2014-01-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus.
Protein Sci., 23, 2014
5XWW
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Substrate-bound Structure of G355T/Q364H mutant of a Ketoreductase from amphotericin Polyketide Synthases
分子名称: AmphB, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl] (2R)-2-methyl-3-oxidanylidene-pentanethioate
著者Liu, C, Zheng, J.
登録日2017-06-30
公開日2018-06-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.
J. Struct. Biol., 203, 2018
7E3Q
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Crystal structure of SAH bound TrmL from Vibrio vulnificus
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (cytidine(34)-2'-O)-methyltransferase
著者Kim, J, Son, J.
登録日2021-02-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of SAH bound TrmL from Vibrio vulnificus
To Be Published
4MJD
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Crystal structure of ketosteroid isomerase fold protein Hmuk_0747
分子名称: Ketosteroid isomerase fold protein Hmuk_0747, MAGNESIUM ION, SODIUM ION
著者Chang, C, Holowicki, J, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2013-09-03
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structure of ketosteroid isomerase fold protein Hmuk_0747
To be Published
7V9M
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Cryo-EM structure of the GHRH-bound human GHRHR splice variant 1 complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Chen, X, Yang, D.H, Wang, M.W.
登録日2021-08-26
公開日2021-10-20
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Constitutive signal bias mediated by the human GHRHR splice variant 1.
Proc.Natl.Acad.Sci.USA, 118, 2021
3L42
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PWWP domain of human bromodomain and PHD finger containing protein 1
分子名称: Peregrin, UNKNOWN ATOM OR ION
著者Tempel, W, Zeng, H, Ni, S, Amaya, M.F, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2009-12-18
公開日2010-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011

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件を2024-07-17に公開中

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