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2P6F

Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors

Summary for 2P6F
Entry DOI10.2210/pdb2p6f/pdb
Related2P6E 2P6G
DescriptorGlycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA, (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE (3 entities in total)
Functional Keywordsantifungal drug, non-peptidic inhibitor, transferase
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationCytoplasm: P14743
Total number of polymer chains6
Total formula weight325570.15
Authors
Wu, J.,Ding, J. (deposition date: 2007-03-18, release date: 2007-06-12, Last modification date: 2024-03-13)
Primary citationWu, J.,Tao, Y.,Zhang, M.,Howard, M.H.,Gutteridge, S.,Ding, J.
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282:22185-22194, 2007
Cited by
PubMed: 17513302
DOI: 10.1074/jbc.M702696200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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