3SKO
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![BU of 3sko by Molmil](/molmil-images/mine/3sko) | Crystal structure of the HLA-B8-A66-FLR, mutant A66 of the HLA B8 | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. | 登録日 | 2011-06-22 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188, 2012
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6OT4
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![BU of 6ot4 by Molmil](/molmil-images/mine/6ot4) | Bimetallic dodecameric cage design 2 (BMC2) from cytochrome cb562 | 分子名称: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | 著者 | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | 登録日 | 2019-05-02 | 公開日 | 2020-01-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Constructing protein polyhedra via orthogonal chemical interactions. Nature, 578, 2020
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6OT7
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![BU of 6ot7 by Molmil](/molmil-images/mine/6ot7) | Bimetallic dodecameric cage design 3 (BMC3) from cytochrome cb562 | 分子名称: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | 著者 | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | 登録日 | 2019-05-02 | 公開日 | 2020-01-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Constructing protein polyhedra via orthogonal chemical interactions. Nature, 578, 2020
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6OT8
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![BU of 6ot8 by Molmil](/molmil-images/mine/6ot8) | Bimetallic hexameric cage design 4 (BMC4) from cytochrome cb562 | 分子名称: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | 著者 | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | 登録日 | 2019-05-02 | 公開日 | 2020-01-29 | 最終更新日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Constructing protein polyhedra via orthogonal chemical interactions. Nature, 578, 2020
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6OUC
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![BU of 6ouc by Molmil](/molmil-images/mine/6ouc) | Asymmetric focsued reconstruction of human norovirus GII.2 Snow Mountain Virus strain VLP asymmetric unit in T=1 symmetry | 分子名称: | Viral protein 1, ZINC ION | 著者 | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | 登録日 | 2019-05-04 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc.Natl.Acad.Sci.USA, 116, 2019
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8W7M
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![BU of 8w7m by Molmil](/molmil-images/mine/8w7m) | Yeast replisome in state V | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (71-mer), ... | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | 登録日 | 2023-08-30 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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2PEH
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![BU of 2peh by Molmil](/molmil-images/mine/2peh) | Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | 分子名称: | Splicing factor 3B subunit 1, Splicing factor 45 | 著者 | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | 登録日 | 2007-04-03 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
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6OUU
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![BU of 6ouu by Molmil](/molmil-images/mine/6ouu) | Symmetric reconstruction of human norovirus GII.4 Minerva strain VLP in T=4 symmetry | 分子名称: | Major capsid protein | 著者 | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | 登録日 | 2019-05-05 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc.Natl.Acad.Sci.USA, 116, 2019
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7WRH
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![BU of 7wrh by Molmil](/molmil-images/mine/7wrh) | Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Han, P, Xie, Y, Qi, J. | 登録日 | 2022-01-26 | 公開日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s. Cell Discov, 8, 2022
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6OVQ
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![BU of 6ovq by Molmil](/molmil-images/mine/6ovq) | Crystal structure of mithramycin 3-side chain keto-reductase MtmW | 分子名称: | GLYCEROL, Putative Side chain reductase | 著者 | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | 登録日 | 2019-05-08 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
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7W5N
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![BU of 7w5n by Molmil](/molmil-images/mine/7w5n) | The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J. | 登録日 | 2021-11-30 | 公開日 | 2023-03-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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6SP8
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![BU of 6sp8 by Molmil](/molmil-images/mine/6sp8) | Structure of hyperstable haloalkane dehalogenase variant DhaA115 prepared by the 'soak-and-freeze' method under 150 bar of krypton pressure | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Haloalkane dehalogenase, ... | 著者 | Chmelova, K, Markova, K, Damborsky, J, Marek, M. | 登録日 | 2019-08-31 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst. Chem Sci, 11, 2020
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7W5K
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![BU of 7w5k by Molmil](/molmil-images/mine/7w5k) | The C296A mutant of L-sorbosone dehydrogenase (SNDH) from Gluconobacter Oxydans WSH-004 | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | 登録日 | 2021-11-30 | 公開日 | 2023-03-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase. Adv Sci, 10, 2023
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6O5I
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![BU of 6o5i by Molmil](/molmil-images/mine/6o5i) | Menin in complex with MI-3454 | 分子名称: | DIMETHYL SULFOXIDE, Menin, SULFATE ION, ... | 著者 | Linhares, B.M, Klossowski, S, Cierpicki, T, Grembecka, J. | 登録日 | 2019-03-03 | 公開日 | 2020-01-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.24025619 Å) | 主引用文献 | Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. J.Clin.Invest., 130, 2020
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4WXX
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6O7K
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![BU of 6o7k by Molmil](/molmil-images/mine/6o7k) | 30S initiation complex | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | 登録日 | 2019-03-08 | 公開日 | 2019-05-29 | 最終更新日 | 2020-01-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature, 570, 2019
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6SQI
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4WEV
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![BU of 4wev by Molmil](/molmil-images/mine/4wev) | Crystal structure of human AKR1B10 complexed with NADP+ and sulindac | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Crespo, I, Porte, S, Pares, X, Farres, J, Podjarny, A. | 登録日 | 2014-09-11 | 公開日 | 2015-01-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.453 Å) | 主引用文献 | Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10. Chem.Biol.Interact., 234, 2015
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6O67
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![BU of 6o67 by Molmil](/molmil-images/mine/6o67) | |
4GLS
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![BU of 4gls by Molmil](/molmil-images/mine/4gls) | Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21 | 分子名称: | D- RFX001, D- Vascular endothelial growth factor-A, DI(HYDROXYETHYL)ETHER, ... | 著者 | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | 登録日 | 2012-08-14 | 公開日 | 2012-09-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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8W6I
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![BU of 8w6i by Molmil](/molmil-images/mine/8w6i) | |
8W7S
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![BU of 8w7s by Molmil](/molmil-images/mine/8w7s) | Yeast replisome in state IV | 分子名称: | Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ... | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D. | 登録日 | 2023-08-31 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (7.39 Å) | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8W6J
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![BU of 8w6j by Molmil](/molmil-images/mine/8w6j) | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | 著者 | Li, J, Xu, X, He, Y, Luo, M. | 登録日 | 2023-08-29 | 公開日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc To Be Published
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4WSR
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![BU of 4wsr by Molmil](/molmil-images/mine/4wsr) | The crystal structure of hemagglutinin form A/chicken/New York/14677-13/1998 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | 著者 | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | 登録日 | 2014-10-28 | 公開日 | 2015-02-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes. J.Virol., 89, 2015
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4WSU
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![BU of 4wsu by Molmil](/molmil-images/mine/4wsu) | The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 3'SLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | 著者 | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | 登録日 | 2014-10-28 | 公開日 | 2015-02-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes. J.Virol., 89, 2015
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