3SKO
 
 | | Crystal structure of the HLA-B8-A66-FLR, mutant A66 of the HLA B8 | | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ... | | 著者 | Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J. | | 登録日 | 2011-06-22 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
J.Immunol., 188, 2012
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6OT4
 | | Bimetallic dodecameric cage design 2 (BMC2) from cytochrome cb562 | | 分子名称: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | | 著者 | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | | 登録日 | 2019-05-02 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
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6OT7
 | | Bimetallic dodecameric cage design 3 (BMC3) from cytochrome cb562 | | 分子名称: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | | 著者 | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | | 登録日 | 2019-05-02 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
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6OT8
 | | Bimetallic hexameric cage design 4 (BMC4) from cytochrome cb562 | | 分子名称: | ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ... | | 著者 | Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A. | | 登録日 | 2019-05-02 | | 公開日 | 2020-01-29 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
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6OUC
 | | Asymmetric focsued reconstruction of human norovirus GII.2 Snow Mountain Virus strain VLP asymmetric unit in T=1 symmetry | | 分子名称: | Viral protein 1, ZINC ION | | 著者 | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | 登録日 | 2019-05-04 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8W7M
 | | Yeast replisome in state V | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (71-mer), ... | | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | | 登録日 | 2023-08-30 | | 公開日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
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2PEH
 | | Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | | 分子名称: | Splicing factor 3B subunit 1, Splicing factor 45 | | 著者 | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | | 登録日 | 2007-04-03 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
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6OUU
 | | Symmetric reconstruction of human norovirus GII.4 Minerva strain VLP in T=4 symmetry | | 分子名称: | Major capsid protein | | 著者 | Jung, J, Grant, T, Thomas, D.R, Diehnelt, C.W, Grigorieff, N, Joshua-Tor, L. | | 登録日 | 2019-05-05 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7WRH
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.1 spike protein in complex with mouse ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | 著者 | Han, P, Xie, Y, Qi, J. | | 登録日 | 2022-01-26 | | 公開日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
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6OVQ
 | | Crystal structure of mithramycin 3-side chain keto-reductase MtmW | | 分子名称: | GLYCEROL, Putative Side chain reductase | | 著者 | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | | 登録日 | 2019-05-08 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis.
Angew.Chem.Int.Ed.Engl., 59, 2020
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7W5N
 | | The crystal structure of the reduced form of Gluconobacter oxydans WSH-004 SNDH | | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Li, D, Hou, X.D, Rao, Y.J, Yin, D.J, Zhou, J.W, Chen, J. | | 登録日 | 2021-11-30 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.988 Å) | | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase.
Adv Sci, 10, 2023
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6SP8
 | | Structure of hyperstable haloalkane dehalogenase variant DhaA115 prepared by the 'soak-and-freeze' method under 150 bar of krypton pressure | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Haloalkane dehalogenase, ... | | 著者 | Chmelova, K, Markova, K, Damborsky, J, Marek, M. | | 登録日 | 2019-08-31 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst.
Chem Sci, 11, 2020
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7W5K
 | | The C296A mutant of L-sorbosone dehydrogenase (SNDH) from Gluconobacter Oxydans WSH-004 | | 分子名称: | L-sorbosone dehydrogenase, NAD(P) dependent, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Li, D, Hou, X.D, Rao, Y.J, Zhou, J.W, Chen, J. | | 登録日 | 2021-11-30 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structural Insight into the Catalytic Mechanisms of an L-Sorbosone Dehydrogenase.
Adv Sci, 10, 2023
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6O5I
 | | Menin in complex with MI-3454 | | 分子名称: | DIMETHYL SULFOXIDE, Menin, SULFATE ION, ... | | 著者 | Linhares, B.M, Klossowski, S, Cierpicki, T, Grembecka, J. | | 登録日 | 2019-03-03 | | 公開日 | 2020-01-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.24025619 Å) | | 主引用文献 | Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.
J.Clin.Invest., 130, 2020
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4WXX
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6O7K
 | | 30S initiation complex | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | | 登録日 | 2019-03-08 | | 公開日 | 2019-05-29 | | 最終更新日 | 2020-01-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
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6SQI
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4WEV
 | | Crystal structure of human AKR1B10 complexed with NADP+ and sulindac | | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid | | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Crespo, I, Porte, S, Pares, X, Farres, J, Podjarny, A. | | 登録日 | 2014-09-11 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.453 Å) | | 主引用文献 | Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10.
Chem.Biol.Interact., 234, 2015
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6O67
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4GLS
 | | Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21 | | 分子名称: | D- RFX001, D- Vascular endothelial growth factor-A, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | | 登録日 | 2012-08-14 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography.
Proc.Natl.Acad.Sci.USA, 109, 2012
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8W6I
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8W7S
 | | Yeast replisome in state IV | | 分子名称: | Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ... | | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D. | | 登録日 | 2023-08-31 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (7.39 Å) | | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
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8W6J
 | | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | | 著者 | Li, J, Xu, X, He, Y, Luo, M. | | 登録日 | 2023-08-29 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc
To Be Published
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4WSR
 | | The crystal structure of hemagglutinin form A/chicken/New York/14677-13/1998 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | 著者 | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | | 登録日 | 2014-10-28 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
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4WSU
 | | The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 3'SLN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | 著者 | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | | 登録日 | 2014-10-28 | | 公開日 | 2015-02-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
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