3SKO
Crystal structure of the HLA-B8-A66-FLR, mutant A66 of the HLA B8
Summary for 3SKO
Entry DOI | 10.2210/pdb3sko/pdb |
Related | 1KGC 1M05 1MI5 3FFC 3SJV 3SKM 3SKN |
Descriptor | HLA class I histocompatibility antigen, B-8 alpha chain, Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, ... (5 entities in total) |
Functional Keywords | t cell receptor, immune system, antigen presentation |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30460 Secreted: P61769 Host nucleus matrix: Q3KST2 |
Total number of polymer chains | 3 |
Total formula weight | 44929.57 |
Authors | Gras, S.,Wilmann, P.G.,Zhenjun, C.,Hanim, H.,Yu Chih, L.,Kjer-Nielsen, L.,Purcell, A.W.,Burrows, S.R.,Mccluskey, J.,Rossjohn, J. (deposition date: 2011-06-22, release date: 2012-02-29, Last modification date: 2023-09-13) |
Primary citation | Gras, S.,Wilmann, P.G.,Chen, Z.,Halim, H.,Liu, Y.C.,Kjer-Nielsen, L.,Purcell, A.W.,Burrows, S.R.,McCluskey, J.,Rossjohn, J. A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188:311-321, 2012 Cited by PubMed: 22140258DOI: 10.4049/jimmunol.1102686 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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