3FFC

Crystal Structure of CF34 TCR in complex with HLA-B8/FLR

Summary for 3FFC

Entry DOI	10.2210/pdb3ffc/pdb
Descriptor	HLA class I histocompatibility antigen, B-8 alpha chain, Beta-2-microglobulin, FLRGRAYGL peptide from an EBV protein, ... (9 entities in total)
Functional Keywords	tcr-peptide-mhc, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	10
Total formula weight	192377.27
Authors	Gras, S.,Burrows, S.R.,Kjer-Nielsen, L.,Clements, C.S.,Liu, Y.C.,Sullivan, L.C.,Brooks, A.G.,Purcell, A.W.,McCluskey, J.,Rossjohn, J. (deposition date: 2008-12-03, release date: 2009-01-27, Last modification date: 2023-11-01)
Primary citation	Gras, S.,Burrows, S.R.,Kjer-Nielsen, L.,Clements, C.S.,Liu, Y.C.,Sullivan, L.C.,Bell, M.J.,Brooks, A.G.,Purcell, A.W.,McCluskey, J.,Rossjohn, J. The shaping of T cell receptor recognition by self-tolerance. Immunity, 30:193-203, 2009 Cited by PubMed: 19167249 DOI: 10.1016/j.immuni.2008.11.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation