3SKM

Crystal structure of the HLA-B8FLRGRAYVL, mutant G8V of the FLR peptide

Summary for 3SKM

Entry DOI	10.2210/pdb3skm/pdb
Related	1KGC 1M05 1MI5 3FFC 3SJV 3SKN 3SKO
Descriptor	HLA class I histocompatibility antigen, B-8 alpha chain, Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, ... (4 entities in total)
Functional Keywords	t cell receptor, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P30460 Secreted: P61769 Host nucleus matrix: Q3KST2
Total number of polymer chains	3
Total formula weight	44903.66
Authors	Gras, S.,Wilmann, P.G.,Zhenjun, C.,Hanim, H.,Yu Chih, L.,Kjer-Nielsen, L.,Purcell, A.W.,Burrows, S.R.,Mccluskey, J.,Rossjohn, J. (deposition date: 2011-06-22, release date: 2012-02-29, Last modification date: 2023-09-13)
Primary citation	Gras, S.,Wilmann, P.G.,Chen, Z.,Halim, H.,Liu, Y.C.,Kjer-Nielsen, L.,Purcell, A.W.,Burrows, S.R.,McCluskey, J.,Rossjohn, J. A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule. J.Immunol., 188:311-321, 2012 Cited by PubMed: 22140258 DOI: 10.4049/jimmunol.1102686 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation