2PEH

Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5

Summary for 2PEH

• Entry DOI: 10.2210/pdb2peh/pdb
• Related: 2PE8
• Descriptor: Splicing factor 45, Splicing factor 3B subunit 1 (3 entities in total)
• Functional Keywords: rrm, uhm, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q96I25; Nucleus speckle: O75533
• Total number of polymer chains: 4
• Total formula weight: 25993.90

Authors

Corsini, L.,Basquin, J.,Hothorn, M.,Sattler, M. (deposition date: 2007-04-03, release date: 2007-06-26, Last modification date: 2023-08-30)

• Primary citation: Corsini, L.,Bonna, S.,Basquin, J.,Hothorn, M.,Scheffzek, K.,Valcarcel, J.,Sattler, M.; U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.; Nat.Struct.Mol.Biol., 14:620-629, 2007; PubMed: 17589525; DOI: 10.1038/nsmb1260

Experimental method

X-RAY DIFFRACTION (2.11 Å)