2PEH
Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Splicing factor 45 | polymer | 105 | 11690.5 | 2 | UniProt (Q96I25) Pfam (PF00076) | Homo sapiens (human) | 45 kDa-splicing factor, RNA-binding motif protein 17 |
| 2 | B, D (C, D) | Splicing factor 3B subunit 1 | polymer | 10 | 1306.5 | 2 | UniProt (O75533) | Spliceosome-associated protein 155, SAP 155, SF3b155, Pre-mRNA-splicing factor SF3b 155 kDa subunit | |
| 3 | E, F, G, H (A, C, B, D) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 301 - 401 (UniProt: Q96I25)
| PDB | External Database | Details |
|---|---|---|
| Gly 297 | - | cloning artifact |
| Ala 298 | - | cloning artifact |
| Met 299 | - | cloning artifact |
| Gly 300 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 25993.9 | |
| All* | Total formula weight | 25993.9 |
