8TRC
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6T7K
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![BU of 6t7k by Molmil](/molmil-images/mine/6t7k) | Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline | 分子名称: | 1,2-ETHANEDIOL, PROLINE, Proline--tRNA ligase, ... | 著者 | Johansson, C, Wang, J, Tye, M, Payne, N.C, Mazitschek, R, Thompson, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. | 登録日 | 2019-10-22 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline To Be Published
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2PD6
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![BU of 2pd6 by Molmil](/molmil-images/mine/2pd6) | Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8 | 分子名称: | Estradiol 17-beta-dehydrogenase 8, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Turnbull, A.P, Salah, E, Gileadi, O, Savitsky, P, Guo, K, Bunkoczi, G, Pike, A.C.W, Ugochukwu, E, Umeano, C, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-03-31 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of human hydroxysteroid dehydrogenase type 8, HSD17B8 To be Published
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4RUG
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4RY0
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![BU of 4ry0 by Molmil](/molmil-images/mine/4ry0) | Crystal structure of ribose transporter solute binding protein RHE_PF00037 from Rhizobium etli CFN 42, TARGET EFI-511357, in complex with D-ribose | 分子名称: | CALCIUM ION, CHLORIDE ION, Probable ribose ABC transporter, ... | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Morisco, L.L, Wasserman, S.R, Chamala, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Lafleur, J, Hillerich, B, Siedel, R.D, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-12-12 | 公開日 | 2014-12-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of Ribose Transporter Solute Binding Protein from Rhizobium Etly, Target Efi-511357 To be Published
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4Z96
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3F6M
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![BU of 3f6m by Molmil](/molmil-images/mine/3f6m) | Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 著者 | Kim, Y, Maltseva, N, Stam, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2008-11-06 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF from Yersinia pestis To be Published
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3F67
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![BU of 3f67 by Molmil](/molmil-images/mine/3f67) | Crystal Structure of Putative Dienelactone Hydrolase from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, FORMIC ACID, ... | 著者 | Kim, Y, Li, H, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-11-05 | 公開日 | 2008-11-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Crystal Structure of Putative Dienelactone Hydrolase from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 To be Published
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6TPR
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![BU of 6tpr by Molmil](/molmil-images/mine/6tpr) | PqsR (MvfR) bound to inhibitory compound 40 | 分子名称: | 2-[(5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-~{N}-(4-pyridin-2-yloxyphenyl)ethanamide, Transcriptional regulator MvfR | 著者 | Richardson, W.K, Emsley, J. | 登録日 | 2019-12-14 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm GrownPseudomonas aeruginosa. Front Chem, 8, 2020
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9AXF
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![BU of 9axf by Molmil](/molmil-images/mine/9axf) | Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-06 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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3TBO
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5HOL
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9AVL
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![BU of 9avl by Molmil](/molmil-images/mine/9avl) | Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs | 分子名称: | (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. | 登録日 | 2024-03-04 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
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6KYT
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4S3F
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![BU of 4s3f by Molmil](/molmil-images/mine/4s3f) | IspG in complex with Inhibitor 8 (compound 1077) | 分子名称: | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, FE3-S4 CLUSTER, but-3-yn-1-yl trihydrogen diphosphate | 著者 | Quitterer, F, Frank, A, Wang, K, Rao, G, O'Dowd, B, Li, J, Guerra, F, Abdel-Azeim, S, Bacher, A, Eppinger, J, Oldfield, E, Groll, M. | 登録日 | 2015-01-26 | 公開日 | 2015-04-29 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE). J.Mol.Biol., 427, 2015
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6KZA
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![BU of 6kza by Molmil](/molmil-images/mine/6kza) | Crystal structure of the complex of the interaction domains of E. coli DnaB helicase and DnaC helicase loader | 分子名称: | DNA replication protein DnaC, Replicative DNA helicase | 著者 | Nagata, K, Okada, A, Ohtsuka, J, Ohkuri, T, Akama, Y, Sakiyama, Y, Miyazaki, E, Horita, S, Katayama, T, Ueda, T, Tanokura, M. | 登録日 | 2019-09-23 | 公開日 | 2019-11-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding. J.Biochem., 167, 2020
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6TU4
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![BU of 6tu4 by Molmil](/molmil-images/mine/6tu4) | Structure of Plasmodium Actin1 filament | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-1, Jasplakinolide, ... | 著者 | Vahokoski, J, Calder, L.J, Lopez, A.J, Rosenthal, P.B, Kursula, I. | 登録日 | 2020-01-02 | 公開日 | 2021-01-13 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | High-resolution structures of malaria parasite actomyosin and actin filaments. Plos Pathog., 18, 2022
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6TEO
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![BU of 6teo by Molmil](/molmil-images/mine/6teo) | Crystal structure of a yeast Snu114-Prp8 complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | 著者 | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | 登録日 | 2019-11-12 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
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3STJ
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![BU of 3stj by Molmil](/molmil-images/mine/3stj) | Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli | 分子名称: | Protease degQ, peptide (UNK) | 著者 | Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T. | 登録日 | 2011-07-11 | 公開日 | 2011-07-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. J.Biol.Chem., 286, 2011
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5HBJ
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![BU of 5hbj by Molmil](/molmil-images/mine/5hbj) | CDK8-CYCC IN COMPLEX WITH 8-[2-Amino-3-chloro-5-(1-methyl-1H-indazol-5-yl)-pyridin-4-yl]-2,8-diaza-spiro[4.5]decan-1-one | 分子名称: | 1,2-ETHANEDIOL, 8-[2-azanyl-3-chloranyl-5-(1-methylindazol-5-yl)pyridin-4-yl]-2,8-diazaspiro[4.5]decan-1-one, Cyclin-C, ... | 著者 | Musil, D, Blagg, J, Mallinger, A. | 登録日 | 2015-12-31 | 公開日 | 2016-02-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. J.Med.Chem., 59, 2016
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3FBK
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![BU of 3fbk by Molmil](/molmil-images/mine/3fbk) | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A | 分子名称: | Regulator of G-protein signaling 3, SULFATE ION | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-11-19 | 公開日 | 2008-12-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the C2 domain of the human regulator of G-protein signaling 3 isoform 6 (RGP3), Northeast Structural Genomics Consortium Target HR5550A To be Published
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5HRK
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3SV1
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![BU of 3sv1 by Molmil](/molmil-images/mine/3sv1) | Crystal structure of APP peptide bound rat Mint2 PARM | 分子名称: | Amyloid beta A4 precursor protein-binding family A member 2, Amyloid beta A4 protein | 著者 | Shen, Y, Long, J, Yan, X, Xie, X. | 登録日 | 2011-07-12 | 公開日 | 2012-07-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Open-closed motion of Mint2 regulates APP metabolism J Mol Cell Biol, 5, 2013
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5HCN
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![BU of 5hcn by Molmil](/molmil-images/mine/5hcn) | GPN-loop GTPase Npa3 in complex with GMPPCP | 分子名称: | GLYCEROL, GPN-loop GTPase 1, LAURIC ACID, ... | 著者 | Niesser, J, Wagner, F.R, Kostrewa, D, Muehlbacher, W, Cramer, P. | 登録日 | 2016-01-04 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. Mol.Cell.Biol., 36, 2015
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6L1M
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