8TRC
mGluR3 in the presence of the antagonist LY 341495 and positive allosteric modulator VU6023326
Summary for 8TRC
Entry DOI | 10.2210/pdb8trc/pdb |
EMDB information | 41577 |
Descriptor | Metabotropic glutamate receptor 3, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine (2 entities in total) |
Functional Keywords | gpcr, synaptic protein, membrane protein |
Biological source | Rattus norvegicus (Norway rat) |
Total number of polymer chains | 2 |
Total formula weight | 207029.85 |
Authors | |
Primary citation | Strauss, A.,Gonzalez-Hernandez, A.J.,Lee, J.,Abreu, N.,Selvakumar, P.,Salas-Estrada, L.,Kristt, M.,Marx, D.C.,Gilliland, K.,Melancon, B.J.,Filizola, M.,Meyerson, J.,Levitz, J. Structural basis of allosteric modulation of metabotropic glutamate receptor activation and desensitization. Biorxiv, 2023 Cited by PubMed: 37645747DOI: 10.1101/2023.08.13.552748 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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